Publications

Original Articles 2012

Wenger A, Englund M, Wirth W, Hudelmaier M, Kwoh K, Eckstein F; for the OAI Investigators
Relationship of 3D meniscal morphology and position with knee pain in subjects with knee osteoarthritis: a pilot study.
European Radiology 22:211-220 (2012)
Haugen IK, Cotofana S, Englund M, Kvien TK, Dreher D, Nevitt M, Lane NE, Eckstein F
Hand joint space narrowing and osteophytes are associated with magnetic resonance imaging-defined knee cartilage thickness and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.
Journal of Rheumatology 39:161-166 (2012)
Guermazi A, Hunter DJ, Li L, Benichou O, Eckstein F, Kwoh CK, Nevitt M, Hayashi D
Different thresholds for detecting osteophytes and joint space narrowing exist between the site investigators and the centralized reader in a multicenter knee osteoarthritis study-data from the Osteoarthritis Initiative.
Skeletal Radiology 41:179-186 (2012)

Original Articles 2011

Hunter DJ, Arden N, Conaghan PG, Eckstein F, Gold G, Grainger A, Guermazi A, Harvey W, Jones G, Hellio Le Graverand MP, Laredo JD, Lo G, Losina E, Mosher TJ,
Roemer F, Zhang W; on behalf of the OARSI OA Imaging Working Group
Definition of osteoarthritis on MRI: results of a Delphi exercise.
Osteoarthritis and Cartilage 19:963-969 (2011)
Hudelmaier M, Glaser C, Pfau C, Eckstein F
Comparison between different implementations of the 3D FLASH sequence for knee cartilage quantification.
Magnetic Resonance Materials in Physics, Biology and Medicine. 2011 Dec 14. [Epub ahead of print]
Siorpaes K, Wenger A, Bloecker K, Wirth W, Hudelmaier M, Eckstein F
Interobserver reproducibility of quantitative meniscus analysis using coronal multiplanar DESS and IWTSE MR imaging.
Magnetic Resonance in Medicine 2011 Aug 29. doi: 10.1002/mrm.23115. [Epub ahead of print]
Eckstein F, Nevitt M, Gimona A, Picha K, Lee JH, Davies RY, Dreher D, Benichou O, Le Graverand MP, Hudelmaier M, Maschek S, Wirth W; Osteoarthritis Initiative Investigators Group
Rates of change and sensitivity to change in cartilage morphology in healthy knees and in knees with mild, moderate, and end-stage radiographic osteoarthritis: Results from 831 participants from the osteoarthritis initiative.
Arthritis Care and Research 63:311-319 (2011)
Bloecker K, Wirth W, Hudelmaier M, Burgkart R, Frobell R, Eckstein F
Morphometric differences between the medial and lateral meniscus in healthy men – a three-dimensional analysis using magnetic resonance imaging.
Cells Tissues Organs 2011[Epub ahead of print]
Bloecker K, Englund M, Wirth W, Hudelmaier M, Burgkart R, Frobell RB, Eckstein F
Revision 1 Size and position of the healthy meniscus, and its Correlation with sex, height, weight, and bone area- a cross-sectional study.
BMC Musculoskeletal Disorders 12:248 (2011)
Hunter DJ, Eckstein F
From joint anatomy to clinical outcomes in osteoarthritis and cartilage repair: summary of the fifth annual osteoarthritis imaging workshop.
Osteoarthritis and Cartilage 19:1263-1269 (2011)
Bogner B, Tockner B, Runge C, Strohmaier C, Trost A, Branka M, Radner W, Kiel JW, Schroedl F, Reitsamer HA The effect of vasopressin on choroidal blood flow, intraocular pressure, and orbital venous pressure in rabbits. Investigative Ophthalmology and Visual Science 52:7134-7140 (2011)
Sidorenko I, Monetti R, Bauer J, Mueller D, Rummeny E, Eckstein F, Matsuura M, Lochmueller EM, Zysset P, Raeth C
Assessing Methods for Characterising Local and Global Structural and Biomechanical Properties of the Trabecular Bone Network.
Current Medicinal Chemistry 18:3402-3409 (2011)
Neuhuber WL, Schrödl F
ANS control of the eye and the iris.
Autonomic Neuroscience 165: 67-79 (2011)
Eckstein F, Le Graverand MP, Charles HC, Hunter DJ, Kraus VB, Sunyer T, Nemirovskyi O, Wyman BT, Buck R; A9001140, investigators
Clinical, radiographic, molecular and MRI-based predictors of cartilage loss in knee osteoarthritis.
Annals of Rheumatic Diseases 70:1223-30 (2011)
Strohmaier C, Werkmeister RM, Bogner B, Runge C, Schroedl F, Brandtner H, Radner W, Schmetterer L, Kiel JW, Grabner G, Reitsamer HA
A novel, microscope based, non-invasive laser Doppler flowmeter for choroidal blood flow assessment.
Experimental Eye Research 92:545-551(2011)
Savage T, Niehoff A, Brüggemann L, Müller M, Zaucke F, Eckstein F, Müller-Lung U, Brüggemann GP
The use of biomarkers to assess the response of cartilage to exercise.
British Journal of Sports Medicine 45:326 (2011)
Mueller TL, Christen D, Sandercott S, Boyd SK, van Rietbergen B, Eckstein F, Lochmüller EM, Müller R, van Lenthe GH
Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population.
Bone 48:1232-1238 (2011)
Wirth W, Buck R, Nevitt M, Le Graverand MP, Benichou O, Dreher D, Davies RY, Lee JH, Picha K, Gimona A, Maschek S, Hudelmaier M, Eckstein F; for the OA Initiative investigators
MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography - data from the OA initiative.
Osteoarthritis and Cartilage 19:689-699 (2011)
Wachsmuth L, Lindhorst E, Wrubel S, Hadzhiyski H, Hudelmaier M, Eckstein F, Chrubasik S
Micro-morphometrical assessment of the effect of harpagophytum procumbens extract on articular cartilage in rabbits with experimental osteoarthritis using magnetic resonance imging.
Phytotherapy Research 25:1133-1140 (2011)
Moisio K, Chang A, Eckstein F, Chmiel JS, Wirth W, Almagor O, Prasad P, Cahue S, Kothari A, Sharma L
Varus-valgus alignment: Reduced risk for subsequent cartilage loss in the less loaded compartment.
Arthritis and Rheumatism 63:1002-1009 (2011)
Mosher TJ, Zhang Z, Reddy R, Boudhar S, Milestone BN, Morrison WB, Kwoh CK, Eckstein F, Witschey WR, Borthakur A
Knee articular cartilage damage in osteoarthritis: Analysis of MR image biomarker reproducibility in ACRIN-PA 4001multicenter trial.
Radiology 258:832-842 (2011)
Niehoff A, Müller M, Brüggemann L, Savage T, Zaucke F, Eckstein F, Müller-Lung U, Brüggemann GP
Deformational behaviour of knee cartilage and changes in serum cartilage oligomeric matrix protein (COMP) after running and drop landing.
Osteoarthritis and Cartilage 19:1003-1010 (2011)
Intema F, Van Roermund PM, Marijnissen AC, Cotofana S, Eckstein F, Castelein RM, Bijlsma JW, Mastbergen SC, Lafeber FP
Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study.
Annals of Rheumatic Diseases 70:1441-1446 (2011)
Eckstein F, Cotofana S, Wirth W, Nevitt M, John MR, Dreher D, Frobell R, Osteoarthritis Initiative Investigators Group
Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: Data from the osteoarthritis initiative.
Arthritis and Rheumatism 63:2257-2267 (2011)
Cotofana S, Eckstein F, Wirth W, Souza RB, Li X, Wyman B, Hellio-Le Graverand MP, Link T, Majumdar S
In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging.
European Radiology 21:1127-1135 (2011)
Inglis D, Wong AK, Eckstein F, Adachi JD, Beattie KA
Multiplanar reconstruction recovers morphological cartilage assessment reproducibility from maloriented coronal MRI scans.
Magnetic Resonance in Medicine 65:790-795 (2011)
Wirth W, Larroque S, Davies RY, Nevitt M, Gimona A, Baribaud F, Lee JH, Benichou O, Wyman BT, Hudelmaier M, Maschek S, Eckstein F; for the OA Initiative investigators
Comparison of one-year versus two-year change in regional cartilage thickness in osteoarthritis. Results from 346 participants from the Osteoarthritis Initiative.
Osteoarthritis and Cartilage 19:74-83 (2011)
Chang A, Moisio K, Chmiel J, Eckstein F, Guermazi A, Almagor O, Cahue S, Wirth W, Prasad P, Sharma L
Subregional effects of meniscal tears on cartilage loss over 2 years in knee osteoarthritis.
Annals of Rheumatic Diseases 70:74-79 (2011)
Buck RJ, Wyman BT, Hellio Le Graverand MP, Hunter D, Vignon E, Wirth W, Eckstein F
Using ordered values of subregional cartilage thickness change increases sensitivity in detecting risk factors for osteoarthritis progression.
Osteoarthritis and Cartilage 19:302-308 (2011)

Original Articles 2010

Hudelmaier M, Wirth W, Himmer M, Ring-Dimitriou S, Sänger A, Eckstein F
Effect of exercise intervention on thigh muscle volume and anatomical cross-sectional areas-Quantitative assessment using MRI.
Magnetic Resonance in Medicine 64:1713-1720 (2010)
Eckstein F, Yang M, Guermazi A, Roemer FW, Hudelmaier M, Picha K, Baribaud F, Wirth W, Felson DT
Reference values and Z-scores for subregional femorotibial cartilage thickness-results from a large population-based sample (Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference cohort.
Osteoarthritis and Cartilage 18:1275-1283 (2010)
Fotinos-Hoyer A, Guermazi A, Jara H, Eckstein F, Ozonoff A, Khard H, Norbash A, Bohndorf K, Roemer F
Assessment of synovitis in the osteoarthritic knee: Comparison between manual segmentation, semiautomated segmentation, and semiquantitative assessment using contrast-enhanced fat-suppressed T-weighted MRI.
Magnetic Resonance in Medicine 64:604-609 (2010)
Schuler B, Fritscher KD, Kuhn V, Eckstein F, Link TM, Schubert R
Assessment of the individual fracture risk of the proximal femur by using statistical appearance models.
Medical Physics 37:2560-2571 (2010)
Hudelmaier M, Wirth W, Wehr B, Kraus V, Wyman BT, Hellio Le Graverand MP, Eckstein F
Femorotibial cartilage morphology: Reproducibility of different metrics and femoral regions, and sensitivity to change in disease.
Cells Tissues Organs 192:340-350 (2010)
Benichou OD, Hunter DJ, Nelson DR, Guermazi A, Eckstein F, Kwoh K, Myers SL, Wirth W, Duryea J; for the OA Initiative investigators
One-year change in radiographic joint space width in patients with unilateral joint space narrowing: data from the Osteoarthritis Initiative.
Arthritis Care and Research 62:924-931 (2010)
Thevenot J, Pulkkinen P, Kuhn V, Eckstein F, Jämsä T
Structural asymmetry between the hips and its relation to experimental fracture type.
Calcified Tissue International 87:203-210 (2010)
Frobell RB, Nevitt MC, Hudelmaier M, Wirth W, Wyman BT, Benichou O, Dreher D, Davies R, Lee JH, Baribaud F, Gimona A, Eckstein F; for the OA Initiative investigators
Femorotibial subchondral bone area and regional cartilage thickness - a cross-sectional description in healthy reference cases and various radiographic stages of osteoarthritis in 1003 knees from the Osteoarthritis Initiative.
Arthritis Care and Research 62:1612-23 (2010)
Koivumäki JE, Thevenot J, Pulkkinen P, Salmi JA, Kuhn V, Lochmüller EM, Link TM, Eckstein F, Jämsä T
Does femoral strain distribution coincide with the occurrence of cervical versus trochanteric hip fractures? An experimental finite element study.
Medical and Biological Engineering and Computing 48:711-717 (2010)
Wirth W, Frobell RB, Souza RB, Li X, Wyman BT, Le Graverand MP, Link TM, Majumdar S, Eckstein F
A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis.
Magnetic Resonance in Medicine 63:1162-1171 (2010)
Frobell RB, Wirth W, Nevitt M, Wyman BT, Benichou O, Dreher D, Davies RY, Lee JH, Baribaud F, Gimona A, Hudelmaier M, Cotofana S, Eckstein F; for the OA Initiative investigators
Presence, location type, and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA Initiative.
Osteoarthritis and Cartilage 18:668-679 (2010)
Vanwanseele B, Eckstein F, Smith RM, Lange AK, Foroughi N, Baker MK, Shnier R, Fiatarone Singh MA
The relationship between knee adduction moment and cartilage and meniscus morphology in women with osteoarthritis.
Osteoarthritis and Cartilage 18:894-901 (2010)
Cotofana S, Hudelmaier M, Wirth W, Himmer M, Ring-Dimitriou S, Sänger AM, Eckstein F
Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women.
European Journal of Applied Physiology 110:91-97 (2010)
Wirth W, Nevitt M, Hellio Le Graverand MP, Benichou O, Dreher D, Davies RY, Lee J, Picha K, Gimona A, Maschek S, Hudelmaier M, Eckstein F; for the OAI investigators
Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols-comparative data from the osteoarthritis initiative (OAI).
Osteoarthritis and Cartilage 18:547-554 (2010)
Buck RJ, Wyman BT, Le Graverand MP, Wirth W, Eckstein F; for the A9001140 Investigators
An efficient subset of morphological measures for articular cartilage in the healthy and diseased human knee.
Magnetic Resonance in Medicine 63:680-690 (2010)
Wirth W, Benichou O, Kwoh CK, Guermazi A, Hunter D, Putz R, Eckstein F; for the OAI Investigators
Spatial patterns of cartilage loss in the medial femoral condyle in osteoarthritic knees: Data from the Osteoarthritis Initiative.
Magnetic Resonance in Medicine 63:574-581 (2010)
Buck RJ, Wyman BT, Hellio Le Graverand MP, Hudelmaier M, Wirth W, Eckstein F; for the A 9001140 investigators
Osteoarthritis may not be a one-way-road of cartilage loss-comparison of spatial patterns of cartilage change between osteoarthritic and healthy knees.
Osteoarthritis and Cartilage 18:329-335 (2010)
Crema MD, Guermazi A, Li L, Nogueira-Barbosa MH, Marra MD, Roemer FW, Eckstein F, Hellio Le Graverand MP, Wyman BT, Hunter DJ
The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period.
Osteoarthritis and Cartilage 18:336-343 (2010)
Cotofana S, Ring-Dimitriou S, Hudelmaier M, Himmer M, Wirth W, Saenger AM, Eckstein F
Effects of exercise intervention on knee morphology in middle-aged women: a longitudinal analysis using magnetic resonance imaging.
Cells Tissues Organs 192:64-72 (2010)
Eckstein F, Wirth W, Hunter DJ, Guermazi A, Kwoh CK, Nelson DR, Benichou O; for the OA Initiative investigators
Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis-data from the Osteoarthritis Initiative (OAI). Osteoarthritis and Cartilage 18:760-768 (2010)
Reichenbach S, Yang M, Eckstein F, Niu J, Hunter DJ, McLennan CE, Guermazi A, Roemer FW, Hudelmaier M, Aliabadi P, Felson DT
Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham Study.
Annals of Rheumatic Diseases 69:143-149 (2010)
Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV, Schnitzer TJ, Vaz A, Wirth W, Eckstein F
Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls-a multicenter study using 3.0 Tesla MRI and Lyon Schuss radiography.
Annals of Rheumatic Diseases 69:155-162 (2010)
Folkesson J, Carballido-Gamio J, Eckstein F, Link TM, Majumdar S
Local bone enhancement fuzzy clustering for segmentation of MR trabecular bone images.
Medical Physics 37:295-302 (2010)
Whitmarsh D, Humbert L, De Craene M, Del Rio Barquero L, Fritscher K, Schubert R, Eckstein F, Link T, Frangi A
3D Bone mineral density distribution and shape reconstruction of the proximal femur from a single simulated DXA image: an in vitro study.
SPIE Medical Imaging Proceedings Manuscript (2010)
Baum T, Carballido-Gamio J, Huber MB, Müller D, Monetti R, Räth C, Eckstein F, Lochmüller EM, Majumdar S, Rummeny EJ, Link TM, Bauer JS
Automated 3D trabecular bone structure analysis of the proximal femur-prediction of biomechanical strength by CT and DXA.
Osteoporosis International 21:1553-1564 (2010)
Schagemann JC, Kurz H, Casper ME, Stone JS, Dadsetan M, Yu-Long S, Mrosek EH, Fitzsimmons JS, O'Driscoll SW, Reinholz GG
The effect of scaffold composition on the early structural characteristics of chondrocytes and expression of adhesion molecules.
Biomaterials 31:2798-2805 (2010)
Mainik F, Quast G, Flade-Kuthe R, Kuthe A, Schroedl F
The preperitoneal loop in inguinal hernia repair following the totally extraperitoneal technique.
Hernia 14:361-367 (2010)
Stübinger K, Brehmer A, Neuhuber WL, Reitsamer H, Nickla D, Schrödl F
Intrinsic choroidal neurons (ICN) in the chicken eye: chemical coding and synaptic input.
Histochemistry and Cell Biology 134:145-157 (2010)
Heindl LM, Hofmann TJ, Schrödl F, Holbach LM, Kruse FE, Cursiefen C
Intraocular Lymphatics in Ciliary Body Melanomas with Extraocular Extension – Functional for Lymphatic Spread?
Archives of Ophthalmology 128:1001-1008 (2010)
Kryschi C, Klein S, Zolk O, Schrödl F
Silicon Quantum Dots Functionalized for siRNA Delivery.
In: Multifunctional Nanoparticle Systems - Coupled Behavior and Applications.
Materials Research Society Symposia Proceedings (2010)

Original Articles 2009

Moisio K, Eckstein F, Chmiel JS, Guermazi A, Prasad P, Almagor O, Song J, Dunlop D, Hudelmaier M, Kothari A, Sharma L
Denuded subchondral bone and knee pain in persons with knee osteoarthritis.
Arthritis and Rheumatism 60:3703-3710 (2009)
Mueller TL, van Lenthe GH, Stauber M, Gratzke C, Eckstein F, Müller R
Regional age and gender differences in architectural measures of bone quality and their correlation to bone mechanical competence in the human radius of an elderly population.
Bone 45:882-891 (2009)
Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Hunter DJ, Williamson JD, Nicklas BJ
The intensive diet and exercise for arthritis (IDEA) trial: design and rationale.
BMC Musculoskeletal Disorders 10:93 (2009)
Thevenot J., Pulkkinnen P., Koivumäki J., Kuhn V., Eckstein F., Jämsä T
Discrimination of cervical and trochanteric hip fractures using radiography-based two-dimensional finite element models.
The Open Bone Journal 1:16-22 (2009)
Eckstein F, Benichou O, Wirth W, Nelson DR, Maschek S, Hudelmaier M, Kwoh CK, Guermazi A, Hunter D; for the OA Initiative investigators
Magnetic resonance imaging-based cartilage loss in painful contralateral knees with and without radiographic joint space narrowing: data from the osteoarthritis initiative.
Arthritis and Rheumatism 61:1218-1225 (2009)
Hunter DJ, Buck R, Vignon E, Eckstein F, Brandt K, Mazzuca SA, Wyman BT, Otterness I, Hellio Le Graverand MP
Relation of regional articular cartilage morphometry and meniscal position by MRI joint space width in knee radiographs.
Osteoarthritis and Cartilage 17:1170-1176 (2009)
Lee T, Choi JB, Schafer BW, Segars WP, Eckstein F, Kuhn V, Beck TJ
Assessing the susceptibility to local buckling at the femoral neck cortex to age-related bone loss.
Annals of Biomedical Engineering 37:1910-1920 (2009)
Eckstein F, Wirth W, Hudelmaier M, Maschek S, Hitzl W, Wyman BT, Nevitt M, Hellio Le Graverand MP, Hunter D; for the OA Initiative investigators
Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the Osteoarthritis Initiative.
Arthritis Research and Therapy 11:R90 (2009)
Buck RJ, Wyman BT, Le Graverand MP, Hudelmaier M, Wirth W, Eckstein F; for the A9001140 Investigators
Does the use of ordered values of subregional change in cartilage thickness improve the detection of disease progression in longitudinal studies of osteoarthritis?
Arthritis and Rheumatism 61:917-924 (2009)
Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV; Schnitzer TJ, Vaz A, Wirth W, Eckstein F
Subregional femorotibial cartilage morphology in women-comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis.
Osteoarthritis and Cartilage 17:1177-1185 (2009)
Andreisek G, White LM, Sussman MS, Kunz M, Hurtig M, Weller I, Essue J, Marks P, Eckstein F
Quantitative MR imaging evaluation of the cartilage thickness and subchondral bone area in patients with ACL-reconstructions 7 years after surgery.
Osteoarthritis and Cartilage 17:871-878 (2009)
Eckstein F, Maschek S, Wirth W, Hudelmaier M, Hitzl W, Wyman B, Nevitt M, Hellio Le Graverand MP; for the OA Initiative investigators
One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort-association with sex, body mass index, symptoms, and radiographic OA status.
Annals of Rheumatic Diseases 68:674-679 (2009)
Eckstein F, Wyman BT, Buck RJ, Wirth W, Maschek S, Hudelmaier M, Hellio Le Graverand MP; for the A9001140 investigators
Longitudinal quantitative MR imaging of cartilage morphology in the presence of gadopentetate dimeglumine (Gd-DTPA).
Magnetic Resonance in Medicine 61:975-980 (2009)
Eckstein F, Hudelmaier M, Cahue S, Marshall M, Sharma L
Medial-to-lateral ratio of tibiofemoral subchondral bone area is adapted to alignment and mechanical load.
Calcified Tissue International 84:86-194 (2009)
Carballido-Gamio J, Krug R, Huber MB, Hyun B, Eckstein F, Majumdar S, Link TM
Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance images.
Magnetic Resonance in Medicine 61:448-456 (2009)
Bauer JS, Monetti R, Krug R, Matsuura M, Mueller D, Eckstein F, Rummeny EJ, Lochmueller EM, Raeth CW, Link TM
Advances of 3T MR imaging in visualizing trabecular bone structure of the calcaneus are partially SNR-independent: analysis using simulated noise in relation to micro-CT, 1.5T MRI, and biomechanical strength.
Journal of Magnetic Resonance Imaging 29:132-140 (2009)
Mueller TL, Stauber M, Kohler T, Eckstein F, Müller R, van Lenthe GH
Non-invasive bone competence analysis by high-resolution pQCT: An in vitro reproducibility study on structural and mechanical properties at the human radius.
Bone 44:364-371 (2009)
Wirth W, Hellio Le Graverand MP, Wyman BT, Maschek S, Hudelmaier M, Hitzl W, Nevitt M, Eckstein F; for the OA Initiative investigators
Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort.
Osteoarthritis and Cartilage 17:291-297 (2009)
Szczerba D, Kurz H, Szekely G
A computational model of intussusceptive microvascular growth and remodeling.
Journal of Theoretical Biology 261:570-583 (2009)
Beck M, Schlabrakowski A, Schroedl F, Neuhuber W, Brehmer A
ChAT and NOS in human myenteric neurons: co-existence and co-absence.
Cell and tissue research 338:37-51 (2009)
Klein S, Zolk O, Fromm MF, Schroedl F, Neuhuber W, Kryschi C
Functionalized silicon quantum dots tailored for targeted siRNA delivery.
Biochemical and biophysical research communities 387:164-168 (2009)
Winnik S, Klinkert M, Kurz H, Zoeller C, Heinke J, Wu Y, Bode C, Patterson C, Moser M
HoxB5 induces endothelial sprouting in vitro and modifies intussusceptive angiogenesis in vivo involving Angiopoietin-2.
Cardiovascular Research 83:558-565 (2009)
Heindl LM, Hofmann TN, Knorr HL, Rummelt C, Schroedl F, Schloetzer-Schrenhardt U, Holbach LM, Naumann GO, Kruse FE, Cursiefen C
Intraocular lymphangiogenesis in malignant melanomas of the ciliary body with extraocular extension.
Investigative ophthalmology and visual science 50:1988-1995 (2009)
Schagemann JC, Erggelet C, Chung HW, Lahm A, Kurz H, Mrosek EH
Cell-laden and cell-free biopolymer hydrogel for the treatment of osteochondral defects in a sheep model.
Tissue Engineering Part A 15:75-82 (2009)
Lindig TM, Kumar V, Kikinis R, Pieper S, Schroedl F, Neuhuber WL, Brehmer A
Spiny versus stubby: 3D reconstruction of human myenteric (type I)neurons.
Histochemistry and Cell Biology 131:1-12 (2009)

Original Articles 2008

Raeth C, Monetti R, Bauer J, Sidorenko I, Müller D, Matsuura M, Lochmüller EM, Zysset P, Eckstein F
Strength through structure: visualization and local assessment of the trabecular bone structure.
New Journal of Physics 10 (2008)
Fritscher K, Schuler B, Link T, Eckstein F, Suhm N, Hänni M, Hengg C, Schubert R
Prediction of biomechanical parameters of the proximal femur using statistical appearance models and support vector regression.
Medical Image Computing and Assisted Intervention 11:568-575 (2008)
Eckstein F, Wirth W, Hudelmaier M, Stein V, Lengfelder V, Cahue S, Marshall M, Prasad P, Sharma L
Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment.
Arthritis and Rheumatism 59:1563-1570 (2008)
Lochmüller EM, Kristin J, Matsuura M, Kuhn V, Hudelmaier M, Link TM, Eckstein F
Measurement of trabecular bone microstructure does not improve prediction of mechanical failure loads at the distal radius compared with bone mass alone.
Calcified Tissue International 83:293-299 (2008)
Beattie KA, Duryea J, Pui M, O´Neill J, Boulos P, Webber CE, Eckstein F, Adachi JD
Minimum joint space width and tibial cartilage morphology in the knees of healthy individuals: a cross-sectional study.
BMC Musculoskeletal Disordorders 9:119 (2008)
Boehm HF, Horng A, Notohamiprodjo M, Eckstein F, Burklein D, Panteleon A, Lutz J, Reiser M
Prediction of the fracture load of whole proximal femur specimens by topological analysis of the mineral distribution in DXA-scan images.
Bone 43:826-831 (2008)
Wirth W, Eckstein F
A technique for regional analysis of femorotibial cartilage thickness based on quantitative magnetic resonance imaging.
IEEE Transactions on Medical Imaging 27:737-744 (2008)
Sharma L, Eckstein F, Song J, Guermazi A, Prasad P, Kapoor D, Cahue S, Marshall M, Hudelmaier M, Dunlop D
Relationship of meniscal damage, meniscal extrusion, malalignment, and joint laxity to subsequent cartilage loss in osteoarthritic knees.
Arthritis and Rheumatism 58:1716-1726 (2008)
Eckstein F, Buck RJ, Burstein D, Charles HC, Crim J, Hudelmaier M, Hunter D, Hutchins G, Jackson C, Byers Kraus V, Lane NE, Link TM, Majumdar S, Mazzuca S,Prasad PV, Schnitzer TJ, Taljanovic MS, Vaz A, Wyman B, Hellio Le Graverand MP
Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multi-center clinical trial.
Annals of Rheumatic Diseases 67:1683-1688 (2008)
Hunter DJ, Niu J, Zhang Y, Lavalley M, McClennan CE, Hudelmaier M, Eckstein F, Felson DT
Premorbid knee OA is not characterized by diffuse thinness: The Framingham Study.
Annals of Rheumatic Diseases 67:1545-1549 (2008)
Lochmüller EM, Pöschl K, Würstlin L, Matsuura M, Müller R, Link TM, Eckstein F
Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density?
Osteoporosis International 19:537-545 (2008)
Pulkkinen P, Jämsä T, Lochmüller EM, Kuhn V, Nieminen MT, Eckstein F
Experimental hip fracture load can be predicted from plain radiography by combined analysis of trabecular bone structure and bone geometry.
Osteoporosis International 19:547-558 (2008)
Matsuura M, Eckstein F, Lochmüller EM, Zysset PK
The role of fabric in the quasi-static compressive mechanical properties of human trabecular bone from various anatomical locations.
Biomechanical Models of Mechanobiology 7:27-42 (2008)
Otterness IG, Le Graverand MP, Eckstein F
Allometric relationships between knee cartilage volume, thickness, surface area and body dimensions.
Osteoarthritis and Cartilage 16:34-40 (2008)
Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller EM, Majumdar S, Link TM
Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT-correlation with biomechanical strength measurement.
Radiology 247:472-81 (2008)
Kurz H, Fehr J, Nitschke R, Burkhardt H
Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and α-smooth muscle actin: relevance for non-sprouting angiogenesis.
Histochemistry and Cell Biology 130:1027-1040 (2008)

Original Articles 2007

Patel PV, Eckstein F, Carballido-Gamio J, Phan C, Matsuura M, Lochmüller EM,Majumdar S, Link TM
Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5T and 3T.
Calcified Tissue International 81:294-304 (2007)
Eckstein F, Kunz M, Schutzer M, Hudelmaier M, Jackson RD, Yu J, Eaton CB, Schneider E; for the OA Initiative investigators
Two year longitudinal change and test-retest-precision of knee cartilage morphology in a pilot study for the osteoarthritis initiative.
Osteoarthritis and Cartilage 15:1326-1332 (2007)
Eckstein F, Buck RJ, Wyman BT, Kotyk JJ, Le Graverand MP, Remmers AE, Evelhoch JL, Hudelmaier M, Charles HC
Quantitative imaging of cartilage morphology at 3.0 Tesla in the presence of gadopentate dimeglumine (Gd-DTPA).
Magnetic Resonance in Medicine 58:402-406 (2007)
Gratzke C, Hudelmaier M, Hitzl W, Glaser C, Eckstein F
Knee cartilage morphologic characteristics and muscle status of professional weight lifters and sprinters: a magnetic resonance imaging study.
American Journal of Sports Medicine 35:1346-13 (2007)
Eckstein F, Matsuura M, Kuhn V, Priemel M, Muller R, Link TM, Lochmüller EM
Sex differences of human trabecular bone microstructure in aging are site-dependent.
Journal of Bone and Mineral Research 22:817-24 (2007)
Otterness IG, Eckstein F
Women has thinner cartilage and smaller joint surfaces than men after adjustment for body height
and weight.
Osteoarthritis and Cartilage 15:666-72 (2007)
Eckstein F, Kunz M, Hudelmaier M, Jackson R, Yu J, Eaton C, Schneider E; for the OA Initiative investigators.
Impact of coil design on the contracts-to-noise, precision and consistency of quantitative cartilage morphometry at 3 Tesla-a Pilot Study for the Osteoarthritis Initiative
Magnetic Resonance in Medicine 57:448-454 (2007)
Inglis D, Pui M, Ioannidis G, Beattie K, Boulos P, Adachi JD, Webber CE, Eckstein F
Accuracy and test-retest precision of quantitative cartilage morphology on a 1.0 T peripheral magnetic resonance imaging system.
Osteoarthritis and Cartilage 15:110-5. (2007)

Original Articels 2006

Hudelmaier M, Glaser C, Hausschild A, Burgkart R, Eckstein F
Effects of joint unloading and reloading on human cartilage morphology and function, muscle cross-sectional areas, and bone density-a quantitative case report.
Journal of Musculoskeletal and Neuronal Interactions 6:284-290 (2006)
Eckstein F, Ateshian G, Burgkart R, Burstein D, Cicuttini F, Dardzinski B, Gray M, Link TM, Majumdar S, Mosher T, Peterfy C, Totterman S, Waterton J, Winalski C, Felson D
Proposal for a nomenclature for magnetic resonance imaging based measures of articular cartilage in osteoarthritis.
Osteoarthritis and Cartilage 14:974-983 (2006)
Pulkkinen P, Eckstein F, Lochmuller EM., Kuhn V, Jamsa T
Association of geometric factors and failure load level with the distribution of cervical vs. trochanteric hip fractures.
Journal of Bone and Mineral Research 21: 895-901 (2006)
Phan CM, Matsuura M, Bauer JS, Dunn TC., Newitt D, Lochmueller EM, Eckstein F, Majumdar S
Link TMTrabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard reference.
Radiology 239: 488-96 (2006)
Bauer J, Müller D, Ambekar A, Dobritz M, Matsuura M, Eckstein F, Rummeny E, Link T
Detection of osteoporotic vertebral fractures using multidetector CT.
Osteoporosis International 17:608-615 (2006)
Eckstein F, Hudelmaier M, Wirth W, Kiefer B, Jackson R, Yu J, Eaton C, Schneider E; for the OA Initiative investigators
Double Echo Steady State (DESS) magnetic resonance imaging of knee articular cartilage at 3 Tesla-a pilot study for the Osteoarthritis Initiative.
Annals of Rheumatic Diseases 65:433-441 (2006)
Bauer JS, Kohlmann S, Eckstein F, Mueller D, Lochmueller EM, Link TM
Structural analysis of trabecular bone of the proximal femur using multislice computed tomography: a comparison with dual x-ray absorptiometry for predicting biomechanical strength in vitro.
Calcified Tissue International 78:78-89 (2006)
Von Eisenhart-Rothe R, Graichen H, Hudelmaier M, Vogl T, Sharma L, Eckstein F
Femorotibial and patellar cartilage loss in patients prior to total knee arthroplasty, heterogeneity and correlation with alignment of the knee.
Annals of Rheumatic Diseases 65:69-73 (2006)
Metz S, Kuhn V, Kettler M, Hudelmaier M, Bonel H, Waldt S, Hollweck R, Renger B, Rummeny E, Link T
Comparison of different radiography systems in an experimental study for detection of forearm fractures and evaluation of the Müller-AO and Frykman classification for distal radius fractures.
Investigative Radiology 41:681-690 (2006)

Original Articles 2005

Boehm H, Eckstein F, Wunderer C, Kuhn V, Lochmueller EM, Schreiber K, Mueller D, Rummeny E, Link T
Improved performance of hip DXA using a novel region of interest in the upper part of the femoral neck: in vitro study using bone strength as a standard reference.
Journal of Clinical Densitometry 8:488-494 (2005)
De Souza R, Matsuura M, Eckstein F, Rawlinson S, Lanyon L, Pitsillides A
Non-invasive axial loading of mouse tibiae of cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element.
Bone 37:810-818 (2005)
Hinterwimmer S, Gotthardt M, Eisenhart-Rothe R, Sauerland S, Siebert M, Vogl T, Eckstein F, Graichen H
In vivo contact areas of the knee in patients with patellar subluxation.
Journal of Biomechanics 38:2095-2101 (2005)
Eckstein F, Buck R, Remmers A, Hudelmaier M, Wirth W, Krauss V, Charles C, Evelhoch J
Accuracy and precision of quantitative assessment of cartilage status with 3.0 Tesla magnetic resonance imaging.
Arthritis and Rheumatism 52:3132-3136 (2005)
Hudelmaier M, Kollstedt A, Lochmüller EM, Kuhn V, Eckstein F, Link TM
Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence.
Osteoporosis International 16:1124-1133 (2005)
Graichen H, Al-Shamari D, Hinterwimmer S, von Eisenhart-Rothe R, Vogl T, Eckstein F
Accuracy of quantitative MRI in the detection of ex vivo focal cartilage defects.
Annals of Rheumatic Diseases 64:1120-5 (2005)
Graichen H, Hinterwimmer S, von Eisenhart-Rothe R, Vogl T, Englmeier KH, Eckstein F
Effect of abducting and adducting muscle activity on glenohumeral translation, scapular kinematics and subacromial space width in vivo.
Journal of Biomechanics 38:755-760 (2005)
Von Eisenhart-Rothe R, Matsen FA 3rd, Eckstein F, Vogl T, Graichen H
Pathomechanics in atraumatic shoulder instability: scapular positioning correlates with humeral head centering.
Clinical Orthopaedics and Related Research 433:82-89 (2005)
Patel PV, Prevrhal S, Bauer SJ, Phan C, Eckstein F, Lochmüller EM, Majumdar S, Link TM
Trabecular bone structure obtained from multislice spiral computed tomography of the calcaneus predicts osteoporotic vertebral deformities.
Journal of Computer Assisted Tomography 29:246-253 (2005)
Eckstein F, Lemberger B, Gratzke C, Hudelmaier M, Glaser C, Englmeier K-H, Reiser M
In vivo cartilage deformation after different types of activity and its dependence on physical training status.
Annals of Rheumatic Diseases 64:291-295 (2005)
McWalter EJ, Wirth W, Siebert M, von Eisenhart-Rothe RM, Hudelmaier M, Wilson DR, Eckstein F
Use of novel interactive input devices for segmentation of articular cartilage from magnetic resonance images.
Osteoarthritis and Cartilage 13:48-53 (2005)

Original Articles 2004

Graichen H, v. Eisenhart-Rothe R, Vogl T, Englmeier KH, Eckstein F
Quantitative assessment of cartilage status in osteoarthritis by quantitative magnetic resonance imaging: technical validation for use in analysis of cartilage volume and further morphologic parameters.
Arthritis and Rheumatism 50:811-816 (2004)
von Eisenhart-Rothe R, Bringmann C, Siebert M, Reiser M, Englmeier KH, Eckstein F, Graichen H
Femoro-tibial and menisco-tibial translation patterns in patients with unilateral anterior cruciate ligament deficiency-a potential cause of secondary meniscal tears.
Journal of Orthopaedic Research 22:275-282 (2004)
Homminga J, van Rietbergen B, Lochmüller E-M, Weinans H, Eckstein F, Huiskes R
Osteoporotic vertebral structure is well adapted to the loads of daily life, but not to infrequent “error” loads.
Bone 34:510-516 (2004)
Hudelmaier M, Kuhn V, Lochmüller E-M, Well H, Priemel M, Link TM, Eckstein F
Can geometry-based parameters from pQCT and material properties from quantitative ultrasound (QUS) improve the prediction of radial bone strength over that by bone mass (DXA)?
Osteoporosis International 15:375-381 (2004)
Eckstein F, Wunderer C, Boehm H., Kuhn V, Priemel M, Link TM, Lochmüller E-M
Reproducibility and side differences of mechanical tests for determining the structural strength of the femur.
Journal of Bone and Mineral Research 19:379-385 (2004)
Vanwanseele B, Eckstein F, Hadwighorst H, Knecht H, Stüssi E, Spaepen A
In vivo precision of quantitative shoulder cartilage measurements and changes after spinal cord injury.
Magnetic Resonance in Medicine 51:1026-1030 (2004)
Eckstein F, Weusten A, Schmidt C, Wehr U, Wanke R, Rambeck W, Wolf E, Mohan S
Longitudinal in vivo effects of growth hormone overexpression on bone in transgenic mice.
Journal of Bone and Mineral Research 19:802-810 (2004)
Bauer J., Issever AS, Fischbeck M, Burghardt A, Eckstein F, Rummeny EJ, Majumdar S, Link TM
Mehrschicht-CT zur Strukturanalyse des trabekulären Knochens-Vergleich mit Mikro CT und biomechanischer Festigkeit.
Fortschritte Röntgenstrahlen (RÖFO) 176:709-718 (2004)
Nägele E, Kuhn V, Vogt H, Link TM, Müller R, Lochmüller E-M, Eckstein F
Technical considerations for microstructural analysis of human trabecular bone from specimens xxcised
at various skeletal sites.
Calcified Tissue International 75:15-22 (2004)
Bonel H, Lochmüller E-M, Well H, Kuhn V, Hudelmaier M, Reiser M, Eckstein F
Multi slice computed tomography of the radius metaphysis-relationship of cortical bone structure with gender, age, osteoporotic status, and mechanical competence.
Journal of Clinical Densitometry 7:169-182 (2004)
Pistoia W, van Rietberger B, Lochmüller E-M, Lill C, Eckstein F, Rüegsegger P
Image-based micro- finite-element modeling for improved distal radius strength diagnosis:
moving from "bench" to "bedside”.
Journal of Clinical Densitometry 7:153-160 (2004)
Eckstein F, Siedek V, Glaser C, Al-Ali D, Englmeier KH, Reiser M, Graichen H
Correlation and sex differences of ankle and knee cartilage morphology determined with quantitative magnetic resonance imaging (qMRI).
Annals of Rheumatic Diseases 63:1490-1495 (2004)
Hinterwimmer S, Krammer M, Krötz M, Glaser C, Baumgart R, Reiser M, Eckstein F
Cartilage atrophy in the knees of patients after seven weeks of partial load bearing.
Arthritis and Rheumatism 50: 2516-2520 (2004)
Eckstein F, Fischbeck M, Kuhn V, Link TM, Priemel M, Lochmüller E-M
Determinants and heterogeneity of mechanical competence throughout the thoracolumbar spine of elderly women and men.
Bone 35: 364-374 (2004)
Link TM, Bauer J, Kollstedt A, Stumpf I, Hudelmaier M, Settles M, Majumdar S, Lochmüller E, Eckstein F
Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best?
Investigative Radiology 39:487-97 (2004)

Original Articles 2003

Hudelmaier M, Glaser C, Hohe J, Englmeier KH, Reiser M, Putz R, Eckstein F
Correlation of knee joint cartilage morphology with muscle cross-sectional areas versus anthropometric variables.
Anatomical Record 270: 175-184 (2003)
Lochmüller E-M, Müller M, Kuhn V, Lill C, Eckstein F
Can novel clinical densitometric techniques replace or improve DXA in predicting bone strength in osteoporosis at the hip and other skeletal sites?
Journal of Bone and Mineral Research 18: 906-912 (2003)
Lill CA, Goldhahn J, Albrecht A, Eckstein F, Gatzka C, Schneider E
Impact of bone density on distal radius fracture patterns and comparison between five different fracture classifications.
Journal of Orthopedic Trauma 17:271-2758 (2003)
Graichen H, Jakob J, v Eisenhart-Rothe R, Englmeier KH, Reiser M, Eckstein F
Validation of cartilage thickness measurements in the human shoulder with quantitative magnetic resonance imaging (qMRI).
Osteoarthritis and Cartilage 11:475-482 (2003)
Schmidt C, Priemel M, Kohler T, Weusten A, Müller R, Amling M, Eckstein F
Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton as compared to histology and micro-computed tomography (µCT).
Journal of Bone and Mineral Research 18:1486-1496 (2003)
van Rietbergen B, Huiskes R, Eckstein F, Ruegsegger P
Trabecular bone tissue strains in the healthy and osteoporotic human femur.
Journal of Bone and Mineral Research 18:1781-1788 (2003)
Krishnan R, Park S, Eckstein F, Ateshian GA
Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homonogeous state of stress.
Journal of Biomechanical Engineering 125:569-577 (2003)
Burgkart R, Glaser C, Hinterwimmer S, Hudelmaier M, Englmeier KH, Reiser M, Eckstein F
Feasibility of T- and Z-scores from MR image data for quantifying cartilage loss in osteoarthritis.
Arthritis and Rheumatism 48:2829-2835 (2003)
Glaser C, Burgkart R, Kutschera A, Englmeier KH, Reiser M, Eckstein F
Femoro-tibial cartilage metrics from coronal MR image data: technique, test-retest reproducibility, and findings in OA.
Magnetic Resonance in Medicine 50:1229-1236 (2003)
Hinterwimmer S, Von Eisenhart-Rothe R, Siebert M., Putz R, Eckstein F, Vogl T, Graichen H
Influence of adducting and abducting muscle forces on the subacromial space width.
Medicine und Science in Sports und Exercise 35:2055-2059 (2003)
Vanwanseele B., Eckstein F, Knecht H, Spaepen A, Stüssi E
Longitudinal analysis of cartilage atrophy in the knees of spinal cord injured patients.
Arthritis and Rheumatism 48:3377-3381 (2003)

Original Articles 2002

Eckstein F, Faber S, Mühlbauer R, Hohe J,,Englmeier K-H, Reiser M, Putz R
Functional adaptation of human joints to mechanical stimuli.
Osteoarthritis and Cartilage 10:44-50 (2002)
Lochmüller E-M, Groll O, Kuhn V, Eckstein F
Prediction of mechanical strength of the proximal femur from densitometric and geometric bone properties in the lower vs. upper limb.
Bone 30:207-216 (2002)
Eckstein F, Lochmüller E-M, Lill C, Kuhn V, Schneider E, Delling G, Müller R
Bone strength at clinically relevant sites displays substantial heterogeneity and is best predicted from site-specific bone densitometry.
Journal of Bone and Mineral Research 17:162-171 (2002)
Al-Ali D, Graichen H , Faber SC, Englmeier K- H, Reiser M
Quantitative cartilage imaging in the human hind foot. Normal values and precision.
Journal of Orthopaedic Research 20:249-256 (2002)
Hohe J, Ateshian G, Reiser M, Englmeier K-H, Eckstein F
Surface size, curvature analysis, and quantitative assessment of knee joint incongruity with MR imaging in vivo.
Magnetic Resonance in Medicine 47:554-561 (2002)
Hohe J, Faber S, Mühlbauer R, Reiser M, Englmeier K-H, Eckstein F
Three-dimensional analysis and visualization of regonal MR signal intensity distribution of articular cartilage.
Medical Engineering and Physics 24:219-227 (2002)
Pistoia W, van Rietberger B, Eckstein F, Lill C, Lochmüller E-M, Rüegsegger P
Estimation of distal radius failure load with micro-FE models on 3D-pQCT images.
Bone 30:842-848 (2002)
Eckstein F, Lochmüller E.-M., Koller B., Wehr U, Weusten A, Rambeck W, Hoeflich A, Wolf E
Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.
Growth Hormone and IGF Research 12:116-126 (2002)
Lochmüller E-M, Bürklein D, Kuhn V, Glaser C, Glüer C-C, Eckstein F
Mechanical strength of the thoracolumbar spine in the elderly- prediction from in situ DXA, QCT, upper and lower limb pQCT, and quantitative ultrasound.
Bone 31:77-84 (2002)
Lochmüller E-M, Lill C, Kuhn V, Schneider E, Eckstein F
Radius bone strength in bending, compression, and falling, and its correlation with clinical densitometry at multiple sites.
Journal of Bone and Mineral Research 17:1629-1638 (2002)
Vanwanseele B, Eckstein F, Knecht H, Stüssi E, Spaepen A
Knee cartilage of spinal cord injured patients displays progressive thinning in the absence of normal joint loading and movement.
Arthritis and Rheumatism 46:2073-2078 (2002)
Eckstein F, Müller S, Faber S, Englmeier K-H, Reiser M, Putz R
Side differences of knee joint cartilage morphology as a function of lower limb dominance.
Osteoarthritis and Cartilage 10:914-921 (2002)
Eckstein F, Pavicic T, Nedbal S, Schmidt C, Wehr U, Weusten A, Rambeck W, Wolf E, Hoeflich A
Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone / IGF-I excess in transgenic mice.
Anatomy and Embryology 206:139-148 (2002)
Eckstein F, Heudorfer L, Faber S, Burgkart R, Englmeier K-H, Reiser M
Long-term and resegmentation precision of quantitative cartilage MR imaging (qMRI).
Osteoarthritis and Cartilage 10:922-927 (2002)

Original Articles 2001

Lochmüller E-M, Jung V, Weusten A, Wehr U, Wolf E, Eckstein F
Precision of high-resolution dual energy X-ray absorptiometry measurements of bone mineral status and body composition in small animal models.
European Cells and Materials 1:43-51 (2001)
Pistoia W, Van Rietbergen B, Eckstein F, Lill C, Lochmüller E-M, Ruegsegger P
Prediction of distal radius failure with microFE models based on 3d-PQCT scans.
Advances in Experimental Medicine and Biology 496:143-151 (2001)
Eckstein F, Winzheimer M, Hohe J, Englmeier K-H, Reiser M
Interindividual variability and correlation among morphological parameters of knee joint cartilage plates.
Osteoarthritis and Cartilage 9:101-111 (2001)
Bürklein D, Lochmüller E-M, Kuhn V, Grimm J, Barkmann R, Müller R, Eckstein F
Correlation of thoracic and lumbar vertebral failure loads and prediction by in-situ vs ex-situ dual X-ray
absorptiometry.
Journal of Biomechanics 35:579-587 (2001)
Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Sex-specific differences of subacromial space width during abduction, with and without muscular activity, and correlation with anthropometric variables.
Journal of Shoulder and Elbow Surgery 10:129-135 (2001)
Lochmüller E-M, Krefting N, Bürklein D, Eckstein F
Effect of fixation, soft-tissues and scan projection on bone mineral measurements with dual energy X-ray absorptiometry (DXA).
Calcified Tissue International 68:140-145 (2001)
Glaser C, Faber S, Eckstein F, Fischer H, Springer V, Heudorfer L, Stammberger T, Englmeier K, Reiser M
Optimization and validation of a rapid high-resolution T1-w 3D Flash waterexcitation MR sequence for the quantitative assessment of articular cartilage volume and thickness.
Magnetic Resonance Imaging 19:177-185 (2001)
Faber SC , Eckstein F, Lukasz S, Mühlbauer R, Hohe J, Englmeier K- H, Reiser M
Gender differences of knee joint cartilage thickness, volume and articular surface areas-assessment with quantitative 3D MR imaging.
Skeletal Radiology 30:144-150 (2001)
Graichen H, Englmeier K, Reiser M, Eckstein F
An in vivo technique for determining 3D muscular moment arms in different joint positions and during muscular activation-application to the Supraspinatus.
Clinical Biomechanics 16:389-394 (2001)
Burgkart R, Glaser C, Hyhlik-Dürr A, Englmeier K-H, Reiser M, Eckstein F
MRI-based assessment of cartilage loss in severe osteoarthritis-accuracy, precision, and diagnostic value.
Arthritis and Rheumatism 44:2072-2077 (2001)
Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Changes of shoulder girdle and supraspiantus motion patterns in patients with impingement syndrome-analysis with open MRI and 3D postprocessing.
Journal of Orthopaedic Research 19:1192-1198 (2001)
Hudelmaier M, Glaser C, Hohe J, Englmeier KH, Reiser M, Putz R, Eckstein F
Age-related changes in the morphology and deformational behavior of knee joint cartilage.
Arthritis and Rheumatism 44:2556-2561 (2001)
Graichen H, Stammberger T, Bonel H, Englmeier K-H, Reiser M, Eckstein F
Einfluß der Muskelaktivität auf das 3D-Bewegungsmuster des Schultergürtels-eine MRT basierte Untersuchung.
Unfallchirurg 104:288-293 (2001)
Bachmeier M, Eckstein F, Kuhn V, Groll O, Lill C A, Lochmüller E-M
Mechanische Festigkeit des distalen Radius unter Biegung und axialem Druck-Korrelation mit der peripheren quantitativen Computertomographie.
Osteologie 10:193-203 (2001)

Original Articles 2000

Eckstein F, Stammberger T, Priebsch J, Englmeier K-H, Reiser M
Effect of gradient and section orientation on quantitative analyses of knee joint cartilage.
Journal of Magnetic Resonance Imaging 11:161-167 (2000)
Graichen H, Stammberger T, Bonel H, Haubner M, Englmeier K-H, Reiser M, Eckstein F
3D MR-based motion analysis of the supraspinatus muscle and adjacent shoulder bones during passive elevation.
Clinical Orthopaedics and Related Research 370:154-163 (2000)
Hyhlik-Dürr A, Faber S, Burgkart R, Stammberger T, Maag K-P, Englmeier K-H, Reiser M, Eckstein F
Precision of tibial cartilage morphometry with a coronal water-excitation MR-sequence.
European Radiology 10:297-303 (2000)
Graichen H, Stammberger T, Bonel H, Englmeier K-H, Reiser M, Eckstein F
Glenohumeral translation during active and passive elevation of the shoulder-a 3D open MRI study.
Journal of Biomechanics 33:609-613 (2000)
Eckstein F, Lemberger B, Stammberger T, Englmeier K-H Reiser M
Effect of static versus dynamic in vivo loading exercises on human patellar cartilage.
Journal of Biomechanics 33:819-825 (2000)
Lochmüller E-M, Miller P, Bürklein D,Wehr U, Rambeck W, Eckstein F
In-situ femoral DEXA compared to ash-weight, bone size and density, and the relationship with mechanical failure loads of the proximal femur.
Osteoporosis International 11:361-367 (2000)
Conzen A, Eckstein F
Quantitative determination of articular pressure in the human shoulder joint.
Journal of Shoulder and Elbow Surgery 9:196-204 (2000)
Mühlbauer R, Lukasz S, Faber S, Stammberger T, Eckstein F
Comparison of knee joint cartilage thickness in triathletes and physically inactive volunteers-3D analysis with magnetic resonance imaging.
American Journal of Sports Medicine 28:541-546 (2000)
Stammberger T, Hohe J, Englmeier K-H, Reiser M, Eckstein F
Elastic registration of 3D cartilage surfaces from MR image data for detecting local changes of the cartilage thickness.
Magnetic Resonance in Medicine 44:592-601 (2000)
Hohe J, Faber S, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
A technique for 3D in vivo quantification of proton density and magnetization transfer coefficients of knee joint cartilage.
Osteoarthritis and Cartilage 8:426-433 (2000)
Cindik E, Willnecker J, Wolf E, Eckstein F
Analyse der femoralen Knocheneigenschaften MT-bGH transgener Mäuse mit der hochauflösenden pQCT. Osteologie 9:85-93 (2000)
Heudorfer L , Hohe J, Faber S, Englmeier K-H, Reiser M, Eckstein F
Präzision MR-basierter Knorpeldicken- und Gelenkflächenmessungen-Verwendung einer schnellen, hochauflösenden Wasseranregungssequenzen und eines semiautomatischen Segmentierungs-Algorithmus.
Biomedizinische Technik 45:304-310 (2000)
Bringmann C, Eckstein F, Bonel H, Englmeier, K-H, Reiser M, Graichen H
Eine neue In-vivo-Technik zur dreidimensionalen Analyse der Translation der Femurkondylen und der menisken unter dem Einfluß antagonistischer Muskelkräfte.
Biomedizinische Technik 45:258-265 (2000)
v Eisenhart-Rothe R, Wiedemann E, Bonel H, Eckstein F, Reiser M, Englmeier K-H, Graichen H
MR-basierte 3D Analyse der glenohumeralen Translation bei Patienten mit Schulterinstabilität.
Zeitschrift für Orthopädie und ihre Grenzgebiete 138:481-486 (2000)

Original Articles 1999

Eckstein F, Merz B, Schön M, Jacobs C R, Putz R
Tension and bending, but not compression alone determine the functional adaptation of subchondral bone in incongruous joints.
Anatomy and Embryology 199:85-97 (1999)
Graichen H, Lochmüller E-M, Wolf E, Langkabel R, Stammberger T, Haubner M, Renner-Müller I, Englmeier K-H, Eckstein F
A non-destructive technique for 3D microstructural phenotypic characterization of bones in genetically altered mice-preliminary data in growth hormone transgenic animals and normal controls.
Anatomy and Embryology 199:39-248 (1999)
Stammberger T, Eckstein F, Englmeier K-H, Reiser M
Determination of 3D cartilage thickness data from MR imaging-computational method and reproducibility in the living.
Magnetic Resonance in Medicine 41:529-536 (1999)
Graichen H, Bonel H, Stammberger T, Haubner M, Rohrer H, Englmeier K-H, Reiser M, Eckstein F
Three-dimensional analysis of the width of the subacromial space in healthy subjects and patients with impingement syndrome.
American Journal of Roentgenology 172:1081-1086 (1999)
Fischer K, Eckstein F, Becker C
Density-based load estimation predicts altered femoral load directions for coxa vara and coxa valga.
Journal of Musculoskeletal Research 3:83-92 (1999)
Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Subacromial space width changes during abduction and rotation-a 3D MR imaging study.
Surgical and Radiologic Anatomy 21:59-64 (1999)
Eckstein F, Tieschky M, Faber S, Englmeier K-H, Reiser M
Functional analysis of articular cartilage deformation, recovery, and fluid flow following dynamic exercise in vivo.
Anatomy and Embryology 200:419-424 (1999)
von Eisenhart-Rothe R, Adam C, Steinlechner M, Müller-Gerbl M, Eckstein F
Quantitative determination of joint incongruity and pressure distribution during simulated gait, and cartilage thickness in the human hip joint.
Journal of Orthopaedic Research 17:532-539 (1999)
Pöpperl G, Lochmüller E-M, Becker H-J, Mall G, Steinlechner M, Eckstein F
Determination of calcaneal ultrasound properties ex-situ: reproducibility, effects of storage, formalin fixation, maceration, and changes in anatomic measurement site.
Calcified Tissue International 65:192-197 (1999)
Stammberger T, Eckstein F, Michaelis M, Englmeier K-H, Reiser M
Interobserver reproducibility of quantitative cartilage measurements: comparsion between B-spline snakes and manual segmentation.
Magnetic Resonance Imaging 17:1033 -1042 (1999)
Lochmüller E-M, Eckstein F, Zeller JB, Steldinger R, Putz R
Comparison of quantitative ultrasound in the human calcaneus with mechanical failure loads of the hip and spine.
Ultrasound in Obstetrics and Gynaecology 14:125-133 (1999)
Herberhold C, Faber S, Stammberger T, Steinlechner M, Putz R, Englmeier K-H, Reiser M, Eckstein F
In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading.
Journal of Biomechanics 32:1287-1295 (1999)
Groll O, Lochmüller E-M, Bachmeier M, Willnecker J, Eckstein F
Precision and intersite-correlation of bone densitometry at the radius, tibia and femur with peripheral quantitative CT S.
Skeletal Radiology 28:696-702 (1999)
Weusten A, Lochmüller E-M, Cindik E, Renner Müller I, Tysarczyk-Niemeyer G, Wolf E, Eckstein F
Femoral bone mass, size and density in male and female growth-hormone transgenic mice.
Transgenics 3:43-50 (1999)
Dietmair S, Putz R, Eckstein F
Spaltlinienmuster des subchondralen Knochens in Gelenken des menschlichen Fußes und der Hand.
Osteologie 8:13-22 (1999)
Vogt S, Eckstein F, Schön M, Putz R
Vorzugsrichtung der Kollagenfibrillen im subchondralen Knochen des Hüft- und Schultergelenks.
Annals of Anatomy 181:181-189 (1999)
Graichen H, Bonel H, Stammberger T, Heuck A, Englmeier K-H, Reiser M, Eckstein F
Eine MR-basierte Technik zur Bestimmung der Weite des subakromialen Raumes am Lebenden mit und ohne Aktivität der Schultermuskulatur.
Zeitschrift für Orthopädie und ihre Grenzgebiete 137:2-6 (1999)
Hyhlik-Dürr A, Burgkart R, Glaser C, Englmeier K-H, Reiser M, Eckstein F
MR-basierte Quantifizierung des Knorpelverlustes bei Osteoarthrose.
Sportorthopädie Sporttraumatologie 15:44-46 (1999)
Lochmüller E-M, Weusten A, Wolf E, Cindik E, Renner Müller I, Eikmeier T, Eckstein F
Geschlechtsspezifische Analyse der Knochenmasse normaler und Wachstumshormon-transgener Mäuse mittels Zweienergie-Röntgen-Absorptiometrie (DXA).
Annals of Anatomy 181:191-198 (1999)
von Eisenhart-Rothe R, Witte H, Steinlechner M, Müller-Gerbl M, Putz R, Eckstein F
Quantitative Bestimmung der Druckverteilung im Hüftgelenk während des Gangzyklus.
Unfallchirurg 102:625-631 (1999)
Zewen S, Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Seitenvergleich und interindividuelle Variabilitdt der akromiohumeralen Distanzmessung in der offenen 3D Magnetresonanztomographie.
Osteologie 8:218-227 (1999)
Eckstein F, Westhoff J, Sittek H, Maag K-P, Haubner M, Faber S, Englmeier K-H, Reiser M
In vivo reproducibility of three-dimensional cartilage volume and thickness measurements with magnetic resonance imaging.
American Journal of Radiology 170:593-597 (1998)

Original Articles 1998

Eckstein F, Milz S, Anetzberger H, Putz R
Thickness of the subchondral mineralization zone in normal male and female and pathologic human patellae.
Journal of Anatomy 192:81-90 (1998)
Adam C, Eckstein F, Milz S, Schulte E, Becker C, Putz R
The distribution of cartilage thickness in the knee joint of old-aged individuals-measurement by A-mode ultrasound.
Clinical Biomechanics 13:1-10 (1998)
Herberhold C, Stammberger T, Faber S, Putz R, Englmeier K-H, Reiser M, Eckstein F
An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint.
Magnetic Resonance in Medicine 39:843-850 (1998)
Eckstein F, Tieschky M, Faber S, Haubner M, Kolem H, Englmeier K-H, Reiser M
Effects of physical exercise on cartilage volume and thickness in vivo-an MR imaging study.
Radiology 207: 243-248 (1998)
Eckstein F, Winzheimer M, Westhoff J, Schnier M, Haubner M, Englmeier K-H, Reiser M, Putz R
Quantitative relationships of normal cartilage volumes of the human knee joint- assessment by magnetic resonance imaging.
Anatomy and Embryology 197:383-390 (1998)
Eckstein F, Schnier M, Haubner M, Priebsch J, Glaser C, Englmeier K-H, Reiser M
Accuracy of three-dimensional knee joint cartilage volume and thickness measurements with MRI.
Clinical Orthopaedics and Related Research 352:137-148 (1998)
Graichen H, Bonel H, Stammberger T, Heuck A, Englmeier K-H, Reiser M, Eckstein F
A technique for determining the spatial relationship between the rotator cuff and the subacromial space in arm abduction using MRI and 3D image processing.
Magnetic Resonance in Medicine 40:640-643 (1998)
Adam C, Eckstein F, Milz S, Putz R
The distribution of cartilage thickness within the joints of the lower limb of elderly individuals.
Journal of Anatomy 193:203-214 (1998)
Lochmüller E-M, Eckstein F, Kaiser D, Zeller JB, Landgraf J, Putz R, Steldinger R
Prediction of vertebral failure loads from spinal and femoral DXA, and calcaneal ultrasound-an in situ analysis with intact soft tissues.
Bone 23:417-424 (1998)
Stammberger T, Herberhold C, Faber S, Englmeier K-H, Reiser M, Eckstein F
A method for quantifying time-dependent changes in MR signal intensity of articular cartilage as a function of tissue deformation in intact joints.
Medical Engineering and Physics 20:741-749 (1998)
Lochmüller E-M, Zeller JB, Kaiser D, Eckstein F, Landgraf J, Putz R, Steldinger R
Correlation of femoral and lumbar DXA and calcaneal ultrasound, measured in situ with intact soft tissues, with the in vitro failure loads of the proximal femur.
Osteoporosis International 8:591-598 (1998)
Zeller JB, Lochmüller E-M, Kaiser D, Eckstein F, Landgraf J, Steldinger R, Putz R
Wertigkeit femoraler und lumbaler Knochendichtemessungen für die Beurteilung der femoralen Bruchlast-eine In-situ-Analyse mittels DXA bei intaktem Weichteilmantel.
Osteologie 7: 37-47 (1998)
Mühlbauer R, Lukasz S, Faber S, Englmeier K- H, Reiser M, Eckstein F
Knorpelvolumina im Kniegelenk von Sportlern und Nicht-Sportlern-eine quantitative Analyse mittels Magnetresonanztomographie.
Sportorthopädie Sporttraumatologie 14:117-121 (1998)
Schnier M, Priebsch J, Faber S, Haubner M, Glaser C, Englmeier K-H, Reiser M, Eckstein F
Relevanz suszeptibilitätsinduzierter geometrischer Fehlkodierungen für die Validität MR-basierter Knorpelvolumen- und -dickenmessungen im Kniegelenk.
Biomedizinische Technik 43:241-246 (1998)
Springer V, Graichen H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Nichtinvasive Analyse des Knorpelvolumens und der Knorpeldicke im menschlichen Ellbogengelenk mittels MRT.
Annals of Anatomy 180: 331-338 (1998)
Schön M, Eckstein F, Vogt S, Huber W, Putz R
Subchondrale Spaltlinien des menschlichen Ellbogen- und Kniegelenks-Ausdruck der Biegung und Zugbeanspruchung des subchondralen Knochens ?
Osteologie 7:77-87 (1998)
Lukasz S, Mühlbauer R, Faber S, Englmeier K- H, Reiser M, Eckstein F
Geschlechtsspezifische Analyse der Knorpelvolumina des Kniegelenks-eine quantitative MRT-basierte Studie.
Annals of Anatomy 180:487-493 (1998)

Original Articles 1997

Eckstein F, Adam C, Sittek H, Becker C, Milz S, Schulte E, Reiser M, Putz R
Non-invasive determination of cartilage thickness throughout joint surfaces using magnetic resonance imaging.
Journal of Biomechanics 30:285-289 (1997)
Englmeier K-H, Haubner M, Lösch A, Eckstein F, Seemann MR, van Eimeren W, Reiser M
Hybrid rendering of multidimensional image data.
Methods of Information in Medicine 36:1-10 (1997)
von Eisenhart-Rothe R, Eckstein F, Müller-Gerbl M, Landgraf J, Rock C, Putz R
Direct comparison of contact areas, contact stress and subchondral mineralization in human hip-joint specimens.
Anatomy and Embryology 195:279-288 (1997)
Milz S, Eckstein F, Putz R
The thickness distribution of the subchondral mineralization zone of the trochlear notch and its correlation with the thickness of the cartilage: an expression of functional adaptation to mechanical stress acting on the humeroulnar joint.
Anatomical Record 248:189-197 (1997)
Merz B, Eckstein F, Hillebrand S, Putz R
Mechanical implications of humero-ulnar incongruity-finite element analysis and experiment.
Journal of Biomechanics 30:713-721 (1997)
Lösch A, Eckstein F, Haubner M, Englmeier K-H
A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI-
Part I: development of a computational method.
Magnetic Resonance Imaging 15:795-804 (1997)
Haubner M, Eckstein F, Lösch A, Schnier M, Sittek H, Becker C, Kolem H, Reiser M, Englmeier K-H
A non-invasive technique for 3-dimensional assessment of articular cartilage thickness based on MRI-
Part II: Validation with CT arthrography.
Magnetic Resonance Imaging 15:805-813 (1997)
Eckstein F, von Eisenhart-Rothe R, Landgraf J, Adam C, Löhe F, Müller-Gerbl M, Putz R
Quantitative Analysis of incongruity, contact and articular cartilage thickness in the human hip joint.
Acta Anatomica 158: 192-204 (1997)
Jacobs C, Eckstein F
Computer simulation of subchondral bone adaptation to mechanical loading in an incongruous joint.
Anatomical Record 249: 317-326 (1997)
Eckstein F, Jacobs C R, Merz R
Mechanobiological adaptation of subchondral bone as a function of joint incongruity and loading.
Medical Engineering and Physics 19: 720-728 (1997)
Tieschky M, Faber S, Haubner M, Kolem H, Schulte E, Englmeier K-H, Reiser M, Eckstein F
Repeatability of patellar cartilage thickness patterns in the living, using a fat-suppressed MRI sequence with short acquisition time and 3D data processing.
Journal of Orthopaedic Research 15:808-813 (1997)
Witte H, Eckstein F, Recknagel S
A calculation of the forces acting on the fossa acetabuli during walking-based on in vivo measurements, kinematic analysis and morphometry.
Acta Anatomica 160:269-280 (1997)
Tieschky M, Eckstein F, Lösch A, Faber S, Haubner M, Kolem H, Englmeier K-H, Putz R, Reiser M
Quantitative Bestimmung von patellaren Knorpelvolumen- und Knorpeldickenänderungen nach dynamischer mechanischer Belastung mittels 3D MR-Chondro-Crassometrie.
Sportorthopädie Sporttraumatologie 13: 118-122 (1997)

Original Articles 1996

Eckstein F, Sittek H, Gavazzeni A, Schulte E, Kiefer B, Milz S, Reiser M, Putz R
Magnetic resonance chondro-crassometry (MR-CCM): a method for accurate determination of articular cartilage thickness?
Magnetic Resonance in Medicine 35:89-96 (1996)
Sittek H, Eckstein F, Gavazzeni A, Milz S, Kiefer B, Schulte E, Reiser M
Assessment of normal patellar cartilage volume and thickness using MRI: an analysis of currently available pulse sequences.
Skeletal Radiology 25:55-62 (1996)
Eckstein F, Merz B, Sittek H, Kolem H, Reiser M, Putz R
Geometry-to-pressure relationship in the human elbow joint-a qualitative analysis using MRI and finite elements.
European Journal of Anatomy 1:23-30 (1996)
Eckstein F, Gavazzeni A, Sittek H, Haubner M, Lösch A, Milz S, Englmeier K, Schulte E, Putz R, Reiser M
Determination of knee-joint cartilage thickness using three-dimensional magnetic resonance chondro crassometry (3D MR-CCM).
Magnetic Resonance in Medicine 36:256-265 (1996)
Münsterer O, Eckstein F, Hahn D, Putz R
Computer-aided 3D assessment of knee joint cartilage with magnetic resonance imaging.
Clinical Biomechanics 11:260-266 (1996)
Löhe F, Eckstein F, Sauer T, Putz R
Structure, strain and function of the transverse acetabular ligament.
Acta Anatomica 157:315-323 (1996)

Original Articles 1995

Eckstein F, Müller-Gerbl M, Steinlechner M, Kierse R, Putz R
Subchondral bone density of the human elbow assessed by computed tomography osteoabsorptiometry-a reflection of the loading history of the joint surfaces.
Journal of Orthopaedic Research 13:268-278 (1995)
Milz S, Eckstein F, Putz R
The thickness of the subchondral plate and its correlation with the thickness of the uncalcified articular cartilage in the human patella.
Anatomy and Embryology 192:437-444 (1995)
Eckstein F, Sittek H, Milz S, Schulte E, Kiefer B, Reiser M, Putz R
The potential of magnetic resonance imaging (MRI) for quantifying articular cartilage thickness-
a methodological study.
Clinical Biomechanics 10:434-440 (1995)
Eckstein F, Löhe F, Hillebrand S, Bergmann M, Schulte E, Milz S, Putz R
Morphomechanics of the humero-ulnar joint Part I: Joint space width and contact areas as a function of load and flexion angle.
Anatomical Record 243:318-326 (1995)
Eckstein F, Merz B, Müller-Gerbl M, Holzknecht N, Pleier M, Putz R
Morphomechanics of the humero-ulnar joint II: Concave incongruity determines the distribution of load and subchondral mineralization.
Anatomical Record 243:327-335 (1995)
Eckstein F, Sittek H, Gavazzeni A, Milz S, Kiefer B, Putz R, Reiser M
Der Kniegelenksknorpel in der Magnetresonanztomographie MR-Chondrovolumetrie (MR-CVM) mittels fettunterdrückter FLASH-3D-Sequenz.
Radiologe 35:87-93 (1995)
Sittek H, Heuck A, Eckstein F, Reiser M
Magnetresonanztomographie bei Traumen des Kniegelenkes.
Radiologe 35:101-108 (1995)
Gavazzeni A, Eckstein F, Sittek H, Milz S, Schulte E, Kiefer B, Putz R, Reiser M
Die Bestimmung der quantitativen Verteilung des hyalinen Knorpelgewebes mittels Magnetresonanztomographie Welches ist die geeignetste Sequenz?
Sportorthopädie Sporttraumatologie 11:176-182 (1995)
Lösch A, Eckstein F, Haubner M, Sittek H, Gavazzeni A, Milz S, Kolem H, Kiefer B, Reiser M, Englmeier K
3D MR-Chondro-Crassometrie-eine Methode zur nicht-invasiven, automatisierten, dreidimensionalen Bestimmung der Knorpeldicke mittels Magnetresonanztomographie.
Sportorthopädie Sporttraumatologie 11:183-186 (1995)

Original Articles 1994

Eckstein F, Löhe F, Müller-Gerbl M, Steinlechner M, Putz R
Stress distribution in the trochlear notch-a model of bicentric load transmission through joints.
Journal of Bone and Joint Surgery 76 B:647-653 (1994)
Eckstein F, Merz B, Schmid P, Putz R
The influence of geometry on the stress distribution in joints-a finite element analysis.
Anatomy and Embryology 189:545-552 (1994)
Eckstein F, Sittek H, Milz S, Putz R, Reiser M
The morphology of articular cartilage assessed by magnetic resonance imaging (MRI)- Reproducibility and anatomical correlation.
Surgical and Radiologic Anatomy 16:429-438 (1994)
Löhe F, Eckstein F, Putz R
Die Beanspruchung des Ligamentum transversum acetabuli unter physiologischer Belastung des Hüftgelenks.
Unfallchirurg 97:445-449 (1994)
Eckstein F, Müller-Gerbl M, Putz R
Die Verteilung der Knorpeldegeneration an der menschlichen Patella in Beziehung zur individuellen subchondralen Mineralisierung.
Zeitschrift für Orthopädie und ihre Grenzgebiete 132:405-411 (1994)

Original Articles 1993

Eckstein F, Löhe F, Schulte E, Müller-Gerbl M, Milz S, Putz R
Physiological incongruity of the humero-ulnar joint: a functional principle of optimized stress distribution acting upon articulating surfaces?
Anatomy and Embryology 188:449-455 (1993)
Eckstein F, Putz R, Müller-Gerbl M, Steinlechner M, Benedetto KP
Cartilage degeneration in the human patellae and its relationship to the mineralisation of the underlying bone-a key to the understanding of chondromalacia patellae and femoropatellar arthrosis ?
Surgical and Radiologic Anatomy 15:279-286 (1993)
Eckstein F, Müller-Gerbl M, Steinlechner M, Benedetto KP, Putz R
Subchondrale Mineralisierungsmuster bei Chondromalacia patellae.
Arthroskopie 6:116-120 (1993)
Eckstein F, Steinlechner M, Müller-Gerbl M, Putz R
Mechanische Beanspruchung und subchondrale Mineralisierung des menschlichen Ellbogengelenks.
Unfallchirurg 96: 399-404 (1993)
Eckstein F, Löhe F, Steinlechner M, Müller-Gerbl M, Putz R
Kontaktflächen des menschlichen Humeroulnargelenks in Abhängigkeit von der Anpreßkraft-ihr Zusammenhang mit subchondraler Mineralisierung und Gelenkflächenmorphologie der Incisura trochlearis.
Annals of Anatomy 175: 445-452 (1993)

Original Articles 1992

Eckstein F, Müller-Gerbl M, Putz R
Distribution of subchondral bone density and cartilage thickness in the human patella.
Journal of Anatomy 180: 425-433 (1992)

Review Articles

Reitsamer HA, Bogner B, Nischler C, Strohmaier C, Radner W, Schroedl F, Runge C, Trost A, Kiel JW
Biological and physical aspects of intraocular pressure.
Klinische Monatsblätter für Augenheilkunde 228:98-103 (2011)
Crema MD, Roemer FW, Marra MD, Burstein D, Gold GE, Eckstein F, Baum T, Mosher TJ, Carrino JA, Guermazi A
Articular cartilage in the knee: current MR imaging techniques and applications in clinical practice and research.
Radiographics 31:37-61(2011)
Eckstein F, Wirth W
Quantitative cartilage imaging in knee osteoarthritis.
Arthritis 2011 Article ID 475684doi:10.1155/2011/475684
Roemer FW, Eckstein F, Guermazi A
Magnetic resonance imaging-based semiquantitative and quantitative assessment in osteoarthritis.
Rheumatic Diseases Clinics of North America 35:521-55 (2009)
Trattnig S, Domayer S, Welsch GW, Mosher T, Eckstein F
MR imaging of cartilage and its repair in the knee-a review.
European Radiology 19:1582-94 (2009)
Eckstein F, Guermazi A, Roemer FW
Quantiative MR imaging of cartilage and trabecular bone in osteoarthritis.
Radiologic Clinics of North America 47: 655-73 (2009)
Hunter DJ, Le Graverand MP, Eckstein F
Radiologic makers of osteoarthritis progression.
Current Opinion in Rheumatology 21:110-7 (2009)
Hunter DJ, Eckstein F
Exercise and osteoarthritis.
Journal of Anatomy 214:197-207 (2009)
Guermazi A, Eckstein F, Hellio Le Graverand-Gastineau M, Conaghan P, Burstein D, Keen H, Roemer F
Osteoarthritis: current role of imaging.
The Medical Clinics of North America 93:101-26 (2009)
Kurz H
Cell lineages and early patterns of embryonic CNS vascularization.
Cell Adhesion & Migration 3:205-210 (2009)
Guermazi A, Burstein D, Conaghan P, Eckstein F, Hellio Le Graverand-Gastineau MP, Keen H, Roemer FW Imaging in osteoarthritis.
Rheumatic Diseases Clinics of North America 2008 34:645-87 (2008)
Augat P, Eckstein F
Quantitative imaging of musculoskeletal tissue
Annual Reviews in Biomedical Engineering 10:369-90 (2008)
Eckstein F, Mosher T, Hunter D
Imaging of knee osteoarthritis: data beyond the beauty
Current Opinion in Rheumatology19:435-443 (2007)
Eckstein F
Future directions in quantitative imaging of osteoarthritis.
European Musculoskeletal Review,Touch Briefings: London (2007)
Eckstein F, Matsuura M, Lochmüller EM
Determinanten mechanischer Kompetenz der Knochen.
Nova Acta Leopoldina NF 94, Nr 348, 89-99 (2007)
Eckstein F
Quantitative magnetic resonance imaging of osteoarthritis.
Future Medicine 1:699-715 (2006)
Eckstein F, Burstein D, Link TM
Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis.
NMR in Biomedicine 19:822-854 (2006)
Eckstein F, Hudelmaier M, Putz R
The effects of exercise on human articular cartilage.
Journal of Anatomy 208:491-512 (2006)
Eckstein F, Cicuttini F, Raynauld J-P, Waterton J C, Peterfy C
Magnetic resonance imaging (MRI) of articular cartilage in knee osteoarthritis (OA): morphological. Assessment Osteoarthritis and Cartilage 14 Suppl A:46-75 (2006)
Peterfy CG, Gold G, Eckstein F, Cicuttini F, Dardzinski B, Stevens R
MRI protocols for whole-organ assessment of the knee in osteoarthritis.
Osteoarthritis and Cartilage 14 Suppl A:95-111 (2006)
Glüer CC, Barkmann R, Hahn HK, Majumdar S, Eckstein F, Nickelsen TN, Bolte H, Dicken V, Heller M
Parametric biomedical imaging--what defines the quality of quantitative radiological approaches?
Fortschritte Röntgenstrahlen (RÖFO) 178:1187-201 (2006)
Eckstein F, Kuhn V, Lochmüller E-M
Strength prediction of the distal radius by bone densitometry-evaluation using biomechanical tests.
Annals of Biomedical Engineering 32:487-503 (2004)
Gray ML, Eckstein F, Peterfy C, Dahlberg L, Kim YJ, Sorensen AG, Smith RL
Towards imaging biomarkers for osteoarthritis.
Clinical Orthopaedics and Related Research 427 (Suppl):S175-181 (2004)
Eckstein F, Glaser C
Measuring cartilage morphology with quantitative magnetic resonance imaging.
Seminars Musculoskeletal Radiology 8:329-353 (2004)
Eckstein F
Non-invasive study of human cartilage structure by MRI.
Methods in Molecular Medicine 101:191-218 (2004)
Lochmüller E-M, Müller R, Eckstein F
Does bone densitometry predict mechanical competence throughout the skeleton?
Menopause Management 12:21-25 (2003)
Eckstein F, Englmeier H
[Editorial] Quantitative image analysis: software systems in drug development trials.
Drug Discovery Today 15:922-923 (2003)
Eckstein F, Englmeier K-H, Reiser M
Quantitative Knorpelanalyse mit der Magnetresonanztomographie (qMRI)-Neue Ära der Arthrosediagnostik ? Zeitschrift für Rheumatologie 61: 250-259 (2002)
Lochmüller E-M, Eckstein F
Biomechanische Tests in der Evaluation osteodensitometrischer Verfahren-Hintergurnd, Übersicht und aktuelle Befunde.
Osteologie 11: 154-177 (2002)
Eckstein F, Englmeier K-H, Reiser M, Putz R
In vivo morphometry and functional analysis of human articular cartilage with quantitative magnetic resonance imaging-from image to data, from data to theory.
Anatomy and Embryology 203:147-173 (2001)
Graichen H, Bonel H, Stammberger T, Englmeier K-H, Reiser M, Eckstein F
Möglichkeiten der offenen MRT für die biomechanische Analyse und funktionelle Diagnostik des Schultergelenks.
Sportorthopädie Sporttraumatologie 15:37-43 (1999)
Eckstein F, Reiser M, Englmeier K-H, Putz R
Knorpel als komplexe Knautschzone-neue Wege der quantitativen Analyse mit der Magnetresonanztomographie (MRT).
Einsichten: Forschung an der Ludwig-Maximilians-Universität München 1/99:10-13 (1999)
Faber S C, Eckstein F, Stammberger T, Hylik-Dürr A, Englmeier K-H, Reiser M
Messung von Knorpelvolumen- und -dicken des Kniegelenks mit der MRT.
Medizin im Bild 5:7-10 (1998)
Eckstein F, Graichen H, Bonel H, Englmeier K-H, Reiser M
Cartilage morphology, function, and degeneration-new quantitative approaches with 3-D MR imaging.
Medical Imaging International 8: 10-19 (1998)
Eckstein F, Reiser M, Englmeier K-H, Putz R
Anatomische und biomechanische Aspekte des Gelenkknorpels; pp 12-20.
In: Knieinstabilität-Knorpelschaden Steinkopf; Darmstadt (1998)
Eckstein F, Faber S, Lösch A, Sittek H, Haubner M, Schnier M, Fischer H, Englmeier K H, Reiser M
Aktuelle Aspekte zu Aufbau, funktioneller Anpassung und der mechanisch bedingten Degeneration des Gelenkknorpels: Neue Perspektiven durch die Magnetresonanztomographie Teil II) Lösungswege mittels eines nichtinvasiven bildgebenden Verfahrens.
Sportorthopädie Sporttraumatologie 13: 28-36 (1997)
Eckstein F, Glaser C, Burgkart R, Putz R
Aktuelle Aspekte zu Aufbau, funktioneller Anpassung und der mechanisch bedingten Degeneration des Gelenkknorpels: Neue Perspektiven durch die Magnetresonanztomographie Teil I) Stand der Forschung und ungelöste Probleme.
Sportorthopädie Sporttraumatologie 12: 197- 206 (1996)

Monographs, books, and book chapters

Tillmann BN, Eckstein F
Knochen, Gelenke, Muskeln.
In: Anatomie; pp. 76-94; Ed. Zilles K, Tilmann BN
Springer; Heidelberg (2010)
Carballido-Gamio J, Eckstein F
Quantitative morphological imaging of the knee joint.
In: Advances in MRI of the knee for Osteoarthritis; pp. 143-184; Ed. Majumdar S
World Scientific; Hackensack, New Jersey (2010)
Schroedl F
Intrinsic choroidal neurons.
In: Neuropeptides in the Eye; pp 169-197; Eds Troger J, Kieselbach G, Bechrakis N.
Research Signpost; Kerala (2009)
Ateshian G, Eckstein F
Quantitative anatomy of diarthrodial joint articular layers.
In: Basic Orthopaedic Biomechanics and Mechano-Biology, 3rd edition; pp. 409-438; Ed. Mow VC, Huiskes R.
Lippincott-Raven; Philadelphia, New York (2005)
Eckstein F
Non-invasive study of human cartilage structure by MRI.
In: Osteoarthritis: methods and protocols; Eds Pastoureau P, De Ceunick F, Sabtini M.
Humana Press; Totowa, New Jersey (2004)
Drenckhahn C, Eckstein F
Skelett- und Muskelsystem; Untere Extremität.
In: Benninghoff, Anatomie, Band 1, 16 Auflage; pp 341-411; Ed. Drenckhahn D.
Urban und Fischer, München (2003)
Eckstein F
Form-Funktions-Analyse des Gelenkknorpels mit quantitativer Magnetresonanztomographie (qMRT)
In: Biologische Systeme: Mechanische Eigenschaften und ihre Adaptation bei körperlicher Belastung; Band 135 der Schriftenreihe der Deutschen Vereinigung für Sportwissenschaft; pp 117-131; Eds. Brüggemann GP, Klapsin GM.
Czwalina Verlag, Hamburg (2003)
Eckstein F, Jacobs C, Merz B
Effects of joint incongruity on articular pressure distribution and subchondral bone remodelling.
Advances in Anatomy, Embryology and Cell Biology Vol 152
Springer; Berlin, Heidelberg, New York (2000)
Glaser C, Burkart R, Englmeier K-H, Reiser M, Eckstein F
Volumen und Dicke des Gelenkknorpels-Quantitative Analyse mit der MRT; pp 39-50
In: Das patellofemorale Schmerzsyndrom (Hrsg: CJ Wirth, M Rudert).
Steinkopf; Darmstadt (2000)
Eckstein F, Reiser M, Englmeier K-H, Putz R
Anatomische und biomechanische Aspekte des Gelenkknorpels; pp 12-20
In: Knieinstabilität-Knorpelschaden.
Steinkopf; Darmstadt (1998)

E-letters

Kurz H
Macrophages and quail CNS angiogenesis.
Blood 2010; 116: http://bloodjournal.hematologylibrary.org/cgi/eletters/116/5/829.