Research programs
A research program is a university unit led by a qualified researcher, established for a specific period of time and serving the purpose of researching and developing aspects of new or established fields of science that correspond to the PMU's research profile.
The following research programs of PMU are currently active:
Research program for molecular therapy of genetic dermatoses
More information about the research program can be found here or on the website of the University Department of Dermatology and Allergology
The research program "Molecular therapy of genetic dermatoses" aims to develop therapies for genetic skin diseases. The main focus is on epidermolysis bullosa - the disease from which the "butterfly children" suffer.
Epidermolysis bullosa (EB) is a genetic dermatosis which is caused by mutations in the genes coding the structural proteins of the skin. If these structural proteins are affected qualitatively or quantitatively or are completely absent, the lightest mechanical loads lead to blistering on the skin and sometimes also on the mucous membranes.
Depending on the level of fissure formation, different sub-forms are distinguished. In the mildest form – EB simplex – it comes to a cytolysis of the basal keratinocytes caused by mutations in, for example, KRT5, KRT14 or PLEC. The junctional form – EB junctionalis – is characterised by the formation of a fissure in the area of lamina lucida and is caused mainly by mutations in COL17A1 or in the coding sequences for LAM-332. The dystrophic EB is characterised by the formation of a fissure in the area of lamina densa and is caused by mutations in COL7A1.
Nano vesicular therapies
This page is currently under construction, but will soon they will provide a lot of interesting information on the research programme "Nano vesicular therapies".
Receptor Biochemistry and Tumor Metabolism
Information on the research program can be found here.
The Receptor Biochemistry and Tumor Metabolism Research Program was established in 2009 and is located within the Research and Special Laboratories of the Department of Pediatrics. Based on the broad expertise of the laboratory, a focus is put on two scientific topics, namely receptor biochemistry and tumor metabolism.
Establishment of a research program
Establishing a research programm is intended to qualify for the establishment of a research institute. The research program can be affiliated as an independent research unit (working group) to a research institute, a core institute, a clinical university institute or a university hospital.
