Paracelsus Medizinische Privatuniversität (PMU)

Research & Innovation
Publications

Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation

#2021
#JOURNAL OF MEDICINAL CHEMISTRY

PMU Authors
Veronika Temml, Daniela Brigitte Schuster

All Authors
K. Neukirch, K. Alsabil, CP Dinh, R. Bilancia, M. Raasch, A. Ville, I. Cerqua, G. Viault, D. Breard, S. Pace, Veronika Temml, E. Brunner, PM Jordan, MC Marques, K. Loeser, A. Gollowitzer, S. Permann, J. Gerstmeier, S. Lorkowski, H. Stuppner, U. Garscha, T. Rodrigues, GJL Bernardes, Daniela Brigitte Schuster, D. Seraphin, P. Richomme, A. Rossi, AS Mosig, F. Roviezzo, O. Werz, JJ Helesbeux, A. Koeberle

Journal association
JOURNAL OF MEDICINAL CHEMISTRY

Abstract

Keywords

DISEASE, DERIVATIVES, ANTIINFLAMMATORY ACTIVITY, HUMAN SERUM, PROSTAGLANDIN E-2 SYNTHASE-1, LIPID MEDIATORS, GARCINOIC ACID, 5-LIPOXYGENASE ACTIVITY, ORTHO-FORMYLATION, E SERIES