Institute of Experimental and Clinical Cell Therapy
Publications

Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron

Melanie Schuerz, Isabel Pagani, Eva Klinglmayr, Heloisa Melo Benirschke, Martin Mayora Neto, Luis J. V. Galietta, Arianna Venturini, Nicoletta Pedemonte, Valeria Capurro, Sandra Laner-Plamberger, Christoph Grabmer, Essi Emminger, Martin Wolf, Marianne Steiner, Cyrus Kohlmetz, Niklas Mayr, Liliia Paniushkina, Katharina Schallmoser, Dirk Strunk, Hans Brandstetter, Martin Hintersteiner, Nigel Temperton, Elisa Vicenzi, Nicole Meisner-Kober , PROTEIN; CELLS; CORONAVIRUS; Ace2; Spike;

Spexin expression in the human bile duct and perihilar cholangiocarcinoma

Sara Huber, Theresia Fitzner, Rene G. Feichtinger, Theo Kraus, Stefanie Gaisbauer, Sarah Hochmann, Karl Sotlar, Barbara Kofler, Martin Varga , NEUROPEPTIDES; SPEXIN; CHOLANGIOCARCINOMA; Cholestasis; Bile duct; Cholangiocytes;

Human Cardiac Microtissues Display Improved Engraftment and Survival in a Porcine Model of Myocardial Infarction

Evelyne Demkes, Aina Cervera-Barea, Patricia Ebner-Peking, Martin Wolf, Sarah Hochmann, Amy S Scheren, Mayke Bijsterveld, C Marlies van Oostveen, Marlijn Jansen, Joyce Visser, Wiebke Triebert, Caroline Halloin, Johannes G G Dobbe, Judith de Vos, Melanie Schürz, Joachim Danmayr, Maurice C G Aalders, Gerard J J Boink, Klaus Neef, Dirk Strunk, Robert Zweigerdt, Saskia C A de Jager, Joost P G Sluijter

Anatomical variations and their association with carpal tunnel syndrome

Michaela Gruber, Agnes Wawrik, Florin Gasser, Barbara Ebner, Philipp Reitbauer, Robert Uzel, Rodolphe Poupardin, Maximilian Mahrhofer, Laurenz Weitgasser, Karl Schwaiger, Gottfried Schaffler, Gottfried Wechselberger, Elisabeth Russe , ULTRASOUND; Anatomical variations; Bifid median nerve; Carpal tunnel syndrome; Persistent arteria mediana; Persistent median artery;

Evaluating the potential of Kalanchoe pinnata, Piper amalago amalago, and other botanicals as economical insecticidal synergists against Anopheles gambiae

Sheena Francis, William Irvine, Lucy Mackenzie-Impoinvil, Lucrecia Vizcaino, Rodolphe Poupardin, Audrey Lenhart, Mark J. I. Paine, Rupika Delgoda , RNA-SEQ; INSECTICIDE; Cyp; Jamaican plants; Kalanchoe (Bryophyllum) pinnata; Mosquitoes; Piper amalago var. amalago; Synergist;

DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders

Ivana Lessel, Anja Baresic, Ivan K Chinn, Jonathan May, Anu Goenka, Kate E Chandler, Jennifer E Posey, Alexandra Afenjar, Luisa Averdunk, Maria Francesca Bedeschi, Thomas Besnard, Rae Brager, Lauren Brick, Melanie Brugger, Theresa Brunet, Susan Byrne, Oscar de la Calle-Martín, Valeria Capra, Paul Cardenas, Céline Chappé, Hey J Chong, Benjamin Cogne, Erin Conboy, Heidi Cope, Thomas Courtin, Wallid Deb, Robertino Dilena, Christèle Dubourg, Magdeldin Elgizouli, Erica Fernandes, Kristi K Fitzgerald, Silvana Gangi, Jaya K George-Abraham, Muge Gucsavas-Calikoglu, Tobias B Haack, Medard Hadonou, Britta Hanker, Irina Hüning, Maria Iascone, Bertrand Isidor, Irma Järvelä, Jay J Jin, Alexander A L Jorge, Dragana Josifova, Ruta Kalinauskiene, Erik-Jan Kamsteeg, Boris Keren, Nicole Maeding, Dirk Strunk, Davor Lessel

The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

Celina Ablinger, Daniel Neureiter, Theresa Mähr, Christian Mayr, Tobias Kiesslich, Nicole Maeding, Irina Valenta, Maximilian Ardelt, Fabian Wilhelm, Elen Neureiter, Markus Ritter, Johanna Pachmayr, Petra Huber-Cantonati , Humans; Cell Proliferation/drug effects; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Biliary Tract Neoplasms/drug therapy; Pyridinium Compounds/pharmacology; Indolizines/pharmacology; Cyclic N-Oxides/pharmacology; Bridged Bicyclo Compounds, Heterocyclic/pharmacology; Apoptosis/drug effects; Cyclin-Dependent Kinases/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Cell Survival/drug effects;

Lack of Effect of Platelet- and Stromal Cell-derived EVs on Inflammation-induced 3D Chondrogenesis

Marko Morávek, Martin Wolf, Sarah Hochmann, Nicole Maeding, Luciana Lopes Pedroso, Antri Stefani, Janine Zwicklhuber, Anna Raninger, Katharina Schallmoser, Dirk Strunk

Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis

Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Bloechl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck , APOPTOSIS; Acute myeloid leukemia; Perk; eIF2 alpha, NLRP3;

BEATS - MIGRANE

Janine Zwicklhuber, Sarah Hochmann, Antri Stefani, Martin Wolf, Rodolphe Poupardin, Nicole Maeding, Stefan Leis, Daniela Weber, Julia Tevini, Barbara Kofler, Elisabeth Russe, Dirk Strunk

Advances in Extracellular Vesicle Research Over The Past Decade

Rodolphe Poupardin, Martin Wolf, Nicole Maeding, Liliia Paniushkina, Sven Geissler, Paolo Bergese, Kenneth W Witwer, Katharina Schallmoser, Gregor Fuhrmann, Dirk Strunk

Minimal information for studies of extracellular vesicles (MISEV2023)

, Joshua A Welsh, Deborah C I Goberdhan, Lorraine O'Driscoll, Edit I Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A P Driedonks, Uta Erdbrügger, Juan M Falcon-Perez, Qing-Ling Fu, Andrew F Hill, Metka Lenassi, Sai Kiang Lim, Mỹ G Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M Bridges, Marco Brucale, Dylan Burger, Randy P Carney, Emanuele Cocucci, Federico Colombo, Rossella Crescitelli, Edveena Hanser, Adrian L Harris, Norman J Haughey, An Hendrix, Alexander R Ivanov, Tijana Jovanovic-Talisman, Nicole A Kruh-Garcia, Vroniqa Ku'ulei-Lyn Faustino, Diego Kyburz, Cecilia Lässer, Kathleen M Lennon, Jan Lötvall, Adam L Maddox, Elena S Martens-Uzunova, Rachel R Mizenko, Lauren A Newman, Dirk Strunk, Martin Wolf , REPRODUCIBILITY; GUIDELINES; EXOSOMES; MICROVESICLES; MICROPARTICLES; Ectosomes; Extracellular particles; Extracellular vesicles; Minimal information requirements; Misev; Rigor; Standardisation;

Galanin System in the Human Bile Duct and Perihilar Cholangiocarcinoma.

Sara Huber, Theresia Fitzner, René Feichtinger, Sarah Hochmann, Theo Kraus, Karl Sotlar, Barbara Kofler, Martin Varga , PATHWAY; Humans; CELLS; GENE; EXPRESSION; RECEPTORS; RESISTANCE; INDUCTION; PROLIFERATION; APOPTOSIS; MOLECULAR-CLONING; Klatskin Tumor/pathology; Bile Ducts/metabolism; Peptide Hormones; Galanin/metabolism; Bile Duct Neoplasms/pathology; Cholestasis;

A Novel Fluorescence-Based Screen of Gene Editing Molecules for Junctional Epidermolysis Bullosa.

Janine Zwicklhuber, Thomas Kocher, Bernadette Liemberger, Stefan Hainzl, Johannes Bischof, Dirk Strunk, Anna Raninger, Iris Karina Gratz, Verena Wally, Christina Guttmann-Gruber, Josefina Piñón Hofbauer, Johann Bauer, Ulrich Koller , COLLAGEN XVII;

The platelet transcriptome and proteome in Alzheimer"s disease and aging: an exploratory cross-sectional study.

Diana M Bessa de Sousa, Rodolphe Poupardin, Saul A Villeda, Adam B Schroer, Thomas Fröhlich, Vanessa Natalie Frey, Wolfgang Staffen, Heike Mrowetz, Barbara Altendorfer, Michael S Unger, Bernhard Iglseder, Bernhard Paulweber, Eugen Trinka, Janne Cadamuro, Martin Drerup, Katharina Schallmoser, Ludwig Aigner, Kathrin Maria Kniewallner , INCREASE; ACTIVATION; EXPRESSION; RECEPTORS; AUTOPHAGY; DEMENTIA; BLOOD; MILD COGNITIVE IMPAIRMENT; MOUSE MODELS; IMMUNOPROTEASOME;

Metformin shows anti-neoplastic properties by inhibition of oxidative phosphorylation and glycolysis in epidermolysis bullosa-associated aggressive cutaneous squamous cell carcinoma.

Tobias Welponer, Daniela Weber, Lisa Trattner, Birgit Tockner, Sepideh Aminzadeh-Gohari, Victoria Leb-Reichl, Anna Kaufmann, Roland Zauner, Monika Wimmer, Verena Wally, Thomas Felder, Dirk Strunk, Ulrich Koller, Johann Bauer, Barbara Kofler, Christina Guttmann-Gruber, J Piñon Hofbauer , RISK; CANCER; HEAD; METABOLISM; HYPOXIA-INDUCIBLE FACTORS; AMPK;

A protein corona around human platelet-derived EVs promotes regenerative functions

Katharina Schallmoser, Fausto Gueths Gomes, André Cronemberger Andrade, Martin Wolf, Sarah Hochmann, Linda Krisch, Nicole Maeding, C. Regl, Rodolphe Poupardin, Patricia Ebner-Peking, C. Huber, N. Meissner-Kober, Dirk Strunk

A Protein Corona around Human Platelet-derived EVs Promotes Regenerative Functions

Fausto Gueths Gomes, Katharina Schallmoser, André Cronemberger Andrade, Martin Wolf, Sarah Hochmann, Linda Krisch, Nicole Maeding, C. Regl, Rodolphe Poupardin, Patricia Ebner-Peking, C. Huber, N. Meissner-Kober, Dirk Strunk

The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells.

Sarah Hochmann, Kristy Ou, Rodolphe Poupardin, Michaela Mittermeir, Martin Textor, Salaheddine Ali, Martin Wolf, Agnes Ellinghaus, Dorit Jacobi, Juri A J Elmiger, Samantha Donsante, Mara Riminucci, Richard Schäfer, Uwe Kornak, Oliver Klein, Katharina Schallmoser, Katharina Schmidt-Bleek, Georg N Duda, Julia K Polansky, Sven Geissler, Dirk Strunk , IN-VITRO; MESENCHYMAL STEM-CELLS; DIFFERENTIATION; REPAIR; BONE-MARROW; SEGMENTATION; SCIENCE; EXPANSION; ENDOCHONDRAL OSSIFICATION;

Triple Therapy with Metformin, Ketogenic Diet, and Metronomic Cyclophosphamide Reduced Tumor Growth in MYCN-Amplified Neuroblastoma Xenografts

Luca Catalano, Sepideh Aminzadeh-Gohari, Daniela Weber, Rodolphe Poupardin, Victoria Stefan, William Smiles, Julia Tevini, René Feichtinger, S. Derdak, M. Bilban, S. Bareswill, MM Heimesaat, Barbara Kofler , CANCER; INFLAMMATION; MICE; METABOLISM; SURVIVAL; GLUCOSE; COMBINATION; FGF21; ANTITUMOR;