Forschung & Innovation
Publikationen

Emerging DNA & RNA editing strategies for the treatment of epidermolysis bullosa

Ulrich Koller, Johann W Bauer , Humans; Epidermolysis Bullosa/therapy; Gene editing; Quality of life; Genetic Therapy; CRISPR-Cas Systems; RNA Editing;

The beneficial impact of ketogenic diets on chemically-induced colitis in mice depends on the diet's lipid composition

Kajs Hadzic, Andras Gregor, Barbara Kofler, Marc Pignitter, Kalina Duszka , INFLAMMATION; NUTRITION; KETOGENIC DIET; COLITIS; Lipids;

Unbiased analysis of knee cartilage thickness change over three years after sprifermin vs. placebo treatment - A post-hoc analysis from the phase 2B FORWARD study

Felix Eckstein, Susanne Maschek, Wolfgang Wirth, Christoph Ladel, Asger Reinstrup Bihlet, Chris Knight, Kenneth Somberg, Luping Zhao , Magnetic resonance imaging; CARTILAGE MORPHOMETRY; Clinical trial; DMOAD (sprifermin); Post treatment efficacy;

Optimizing designs in clinical trials with an application in treatment of Epidermolysis bullosa simplex, a rare genetic skin disease

Joakim Nyberg, Andrew C. Hooker, Georg Zimmermann, Johan Verbeeck, Martin Geroldinger, Konstantin Emil Thiel, Geert Molenberghs, Martin Laimer, Verena Wally , Epidermolysis bullosa simplex; Clinical trial design; D-optimal; Optimal design;

Challenges in the diagnosis of patients with nonsyndromic hearing loss, enlarged vestibular aqueduct and Pendred syndrome.

Marek Sklenár, Silvia Borecká, Lukás Varga, Emanuele Bernardinelli, Diana Ugorová, Silvia Dossena, Daniela Gasperiková

Exploring the potential of routine serological markers in predicting neurological outcomes in spinal cord injury

Jan Matthias, Louis P. Lukas, Sarah C. Brueningk, Doris Maier, Orpheus Mach, Lukas Grassner, John L. K. Kramer, Lucie Bourguignon, Catherine R. Jutzeler , Spinal cord injury; Recovery prediction; Serological markers;

Living with Pompe disease

Moritz Ilan Truninger, Helene Werner, Markus Andreas Landolt, Andreas Hahn, Julia B. Hennermann, Florian B. Lagler, Dorothea Moeslinger, Charlotte Pfrimmer, Marianne Rohrbach, Martina Huemer , MUSCLE WEAKNESS; CONTENT VALIDITY; Concept elicitation interviews; Content analysis; Functioning, disability, and health; Health-related quality of life; Inborn errors of metabolism; Lysosomal storage diseases; Pediatric patients; Qualitative analysis;

Lack of Effect of Platelet- and Stromal Cell-derived EVs on Inflammation-induced 3D Chondrogenesis

Marko Morávek, Martin Wolf, Sarah Hochmann, Nicole Maeding, Luciana Lopes Pedroso, Antri Stefani, Janine Zwicklhuber, Anna Raninger, Katharina Schallmoser, Dirk Strunk

The leukotriene receptor antagonist montelukast as a potential therapeutic adjuvant in multiple sclerosis - a review

Frank Pietrantonio, Alex Serreqi, Horst Zerbe, Per Svenningsson, Ludwig Aigner , REGENERATION; RESTORATION; NEUROINFLAMMATION; REMYELINATION; Drug development;

Anion exchanger 1/AE1 function is compromised in red blood cells from prediabetic subjects: beneficial effects of finger lime (Citrus australasica, Faustrime cultivar) juice extract

Alessia Remigante, S. Spinelli, E. Straface, D. Caruso, Silvia Dossena, Rossana Morabito, Angela Marino

Melatonin restores Kv3.1/KCNC1 channel function in an oxidative stress-related model of cellular aging.

Alessia Remigante, S. Spinelli, Raffaella Liuni, Angela Marino, Rossana Morabito, Silvia Dossena

Melatonin restores Kv3.1/KCNC1 channel function in an oxidative stress-related model of cellular aging.

Alessia Remigante, S. Spinelli, Raffaella Liuni, Angela Marino, Rossana Morabito, Silvia Dossena

Anion exchanger 1/AE1 function is compromised in red blood cells from prediabetic subjects: beneficial effects of finger lime (Citrus australasica, Faustrime cultivar) juice extract

Alessia Remigante, S. Spinelli, E. Straface, D. Caruso, Silvia Dossena, Rossana Morabito, Angela Marino

Role of Multistate Models to Predict Patency, Limb Salvage, and Survival

Wolfgang Hitzl, Michaela Kluckner, Manuela Pilz, Mathias Opperer, Klaus Linni, Patrick Nierlich, Florian K Enzmann

Editorial

Stefano Palermi, Josef Niebauer, Alessandro Biffi , CARDIOVASCULAR PREVENTION; Cardiovascular disease; Corporate health check up; Corporate well-being programs; Corporate wellness programs;

Training Intensity Distribution of a 7-Day HIIT Shock Microcycle

Tilmann Strepp, Julia C. Blumkaitis, Mahdi Sareban, Thomas Leonhard Stoeggl, Nils Haller , Athlete's heart; Block training; Cardiac remodeling; Heart rate; Polarized; Pyramidal; Running power; Running velocity; Time-in-zone;

Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis

Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Bloechl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck , APOPTOSIS; Acute myeloid leukemia; Perk; eIF2 alpha, NLRP3;

Biomechanical Comparison of Three Modified Kessler Techniques for Flexor Tendon Repair: Implications in Surgical Practice and Early Active Mobilization

Marlies Schellnegger, Alvin C. Lin, Judith Christine Julie Holzer-Geissler, Annika Haenel, Felix Pirrung, Andrzej Hecker, Lars-Peter Kamolz, Niels Hammer, Werner Girsch

Evaluation of an automated laminar cartilage T2 relaxation time analysis method in an early osteoarthritis model

Wolfgang Wirth, Susanne Maschek, Anna Wisser, Jana Eder, Christian F Baumgartner, Akshay Chaudhari, Francis Berenbaum, Felix Eckstein,

Sexual dimorphism in peri-articular tissue anatomy – More keys to understanding sex-differences in osteoarthritis?

Felix Eckstein, Reinhard Putz, Wolfgang Wirth