Institut für Rehabilitation, Transition und Palliation von neurologisch kranken Kindern
Publikationen

Orthotic bracing to treat equinus in children with spastic cerebral palsy

Claudia Oestreich, Harald Boehm, Matthias Hoesl, Leonhard Doederlein, Daniela Lewens, Chakravarthy U. Dussa, Renate Oberhoffer-Fritz , GAIT ANALYSIS; Ankle-foot orthoses;

Frontal Plane Knee Kinematics and Kinetics During Gait in Children and Youth with Achondroplasia-Correspondence with Static X-Ray Images and Relevance to Symptoms

Matthias Hoesl, Antonia Thamm, Faik Kamel Afifi, Sean Nader , KNEE; VARUS; VALGUS; ACHONDROPLASIA; GAIT ANALYSIS; RADIOLOGY;

Subacute Degeneration of Fibers After Vertical Parasagittal Hemispherotomy

Markus Hittinger, Till Hartlieb, Dieter Henrik Heiland, Pamela Heiland, Tom Pieper, Martin Staudt, Ansgar Berlis, Manfred Kudernatsch, Irina Mader , Humans; Male; Female; Retrospective Studies; CHILD; ADOLESCENT; Child, Preschool; Infant; ADULT; Hemispherectomy/methods; Diffusion Magnetic Resonance Imaging/methods; Postoperative Complications/diagnostic imaging; Wallerian Degeneration/diagnostic imaging;

Epileptiform discharges in the context of self-limited pediatric focal epilepsy (EDSelFEC) in pediatric hemispherotomy patients

Oana Tarta-Arsene, Peter Winkler, Tom Pieper, Till Hartlieb, Andrea Zsoter, Irina Stan, Manfred Kudernatsch, Steffen Berweck, Hans Holthausen , EPILEPSY SURGERY; HEMISPHERECTOMY; Cerebral palsy; Porencephalic cyst; Self-limited epilepsy; White matter damage;

Phenotypic traits and family history in patients with 22q11.2 deletion syndrome and generalized epilepsy

Emanuele Cerulli Irelli, Martina Fanella, Boris Chaumette, Carolina Putotto, Cyril Mignot, Adolfo Mazzeo, Johannes R. Lemke, Antonella Riva, Tommaso Accinni, Cecile Louveau, Agnese Giovannetti, Flaminia Pugnaloni, Martine Gavaret, Fabio Di Fabio, Francesco Fortunato, Thomas Dorn, Edoardo Ferlazzo, Antonio Gambardella, Georgia Ramantani, Biagio Orlando, Anton Iftimovici, Francesca F. Operto, Federica Pulvirenti, Gerhard Kluger, Viviana Caputo, Pasquale Striano, Carlo Di Bonaventura , INTELLECTUAL DISABILITY; Genetic generalized epilepsy; Myoclonic; Neuropsychiatric; Psychosis;

Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome

Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani , Humans; Female; CHILD; ADOLESCENT; Child, Preschool; Infant; Monosaccharide Transport Proteins/deficiency; Infant, Newborn; Treatment Failure; Diet, Ketogenic; Carbohydrate Metabolism, Inborn Errors/diet therapy; Drug Resistant Epilepsy/diet therapy; Glucose Transporter Type 1/deficiency;

Analysis of 1386 epileptogenic brain lesions reveals association with <i>DYRK1A</i> and <i>EGFR</i>

Christian M. Bosselmann, Costin Leu, Tobias Bruenger, Lucas Hoffmann, Sara Baldassari, Mathilde Chipaux, Roland Coras, Katja Kobow, Hajo Hamer, Daniel Delev, Karl Roessler, Christian G. Bien, Thilo Kalbhenn, Tom Pieper, Till Hartlieb, Kerstin Becker, Lisa Ferguson, Robyn M. Busch, Stephanie Baulac, Peter Nuernberg, Imad Najm, Ingmar Bluemcke, Dennis Lal , CANCER; SYSTEM; EPILEPSY; SOMATIC MUTATIONS; GROWTH-FACTOR RECEPTOR; Reference panel; Pathogenicity; Frequencies;

Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes

, Siwei Chen, Bassel W. Abou-Khalil, Zaid Afawi, Quratulain Zulfiqar Ali, Elisabetta Amadori, Alison Anderson, Joe Anderson, Danielle M. Andrade, Grazia Annesi, Mutluay Arslan, Pauls Auce, Melanie Bahlo, Mark D. Baker, Ganna Balagura, Simona Balestrini, Eric Banks, Carmen Barba, Karen Barboza, Fabrice Bartolomei, Nick Bass, Larry W. Baum, Tobias H. Baumgartner, Betuel Baykan, Nerses Bebek, Felicitas Becker, Caitlin A. Bennett, Ahmad Beydoun, Claudia Bianchini, Francesca Bisulli, Douglas Blackwood, Ilan Blatt, Ingo Borggraefe, Christian Bosselmann, Vera Braatz, Harrison Brand, Knut Brockmann, Russell J. Buono, Robyn M. Busch, S. Hande Caglayan, Laura Canafoglia, Christina Canavati, Barbara Castellotti, Gianpiero L. Cavalleri, Felecia Cerrato, Francine Chassoux, Christina Cherian, Stacey S. Cherny, Ching-Lung Cheung, I-Jun Chou, Gerhard Kluger , MUTATIONS; VARIANTS; INTELLECTUAL DISABILITY; Kansl1 cause; Lead;

Hans Berger and 100 years of the electroencephalogram

Johannes R. Lemke, Gerhard Kluger, Guenter Kramer , EEG; Medical history; National socialism; Psychiatry Jena; Biograph Hans Berger;

Characterization of the Epileptogenic Phenotype and Response to Antiseizure Medications in Lissencephaly Patients

Christiane R. Proepper, Sofia M. Schuetz, Lisa-Maria Schwarz, Katja von Au, Thomas Bast, Nathalie Beaud, Ingo Borggraefe, Friedrich Bosch, Joerg Budde, Melanie Busse, Jena Chung, Otfried Debus, Katharina Diepold, Thomas Fries, Gero von Gersdorff, Martin Haeussler, Andreas Hahn, Till Hartlieb, Ralf Heiming, Peter Herkenrath, Gerhard Kluger, Jonas H. Kreth, Gerhard Kurlemann, Peter Moeller, Deborah J. Morris-Rosendahl, Axel Panzer, Heike Philippi, Sophia Ruegner, Carolina Toepfer, Silvia Vieker, Adelheid Wiemer-Kruel, Anika Winter, Gerhard Schuierer, Ute Hehr, Tobias Geis , NEURONAL MIGRATION; Dcx; Lis1/pafah1b1; Antiseizure medication; Epileptic spasms; Lissencephaly;

Corrigendum to "Autoantibody status, neuroradiological and clinical findings in children with acute cerebellitis" [Eur. J. Paediatr. Neurol. 47 (2023) 118-130]

L. Quack, S. Glatter, A. Wegener-Panzer, R. Cleaveland, A. Bertolini, V. Endmayr, R. Seidl, M. Breu, E. Wendel, M. Schimmel, M. Baumann, M. Rauchenzauner, M. Pritsch, N. Boy, T. Muralter, G. Kluger, C. Makoswski, V. Kraus, S. Leiz, C. Loehr-Nilles, J. H. Kreth, S. Braig, S. Schilling, J. Kern, C. Blank, B. Tro Baumann, S. Vieth, M. Wallot, M. Reindl, H. Ringl, K. P. Wandinger, F. Leypoldt, R. Hoftberger, K. Rostasy

Providing quality care for people with CDKL5 deficiency disorder

Sam Amin, Rikke S Møller, Angel Aledo-Serrano, Alexis Arzimanoglou, Patrick Bager, Sergiusz Jóźwiak, Gerhard Josef Kluger, Sandra López-Cabeza, Rima Nabbout, Carol-Anne Partridge, Susanne Schubert-Bast, Nicola Specchio, Reetta Kälviäinen

Instrumented Balance Error Scoring System in Children and Adolescents-A Cross Sectional Study

Nils K T Schönberg, Julius Poppel, David Howell, Johanna Wagner, Michael Höfinger, Nicole Fabri, Elena M Bonke, Philine Rojczyk, Matthias Hösl, Lorenz Kiwull, Sebastian A Schröder, Astrid Blaschek, Katharina Vill, Inga K Koerte, Doreen Huppert, Florian Heinen, Michaela V Bonfert

Outcome of Epilepsy Surgery in MRI-Negative Patients Without Histopathologic Abnormalities in the Resected Tissue

Maurits W. Sanders, Iskander Van der Wolf, Floor E. Jansen, Eleonora Aronica, Christoph Helmstaedter, Attila Racz, Rainer Surges, Alexander Grote, Albert J. Becker, Sylvain Rheims, Helene Catenoix, John S. Duncan, Jane De Tisi, Thomas S. Jacques, J. Helen Cross, Reetta Kalviainen, Tuomas Rauramaa, Francine Chassoux, Bertrand C. Devaux, Giancarlo Di Gennaro, Vincenzo Esposito, Istvan Bodi, Mrinalini Honavar, Christian G. Bien, Thomas Cloppenborg, Roland Coras, Hajo M. Hamer, Petr Marusic, Adam Kalina, Tom Pieper, Manfred Kudernatsch, Till S. Hartlieb, Tim J. Von Oertzen, Martin Aichholzer, Georg Dorfmuller, Mathilde Chipaux, Soheyl Noachtar, Elisabeth Kaufmann, Andreas Schulze-Bonhage, Christian F. Scheiwe, Cigdem OEzkara, Thomas Grunwald, Kristina Koenig, Renzo Guerrini, Carmen Barba, Anna Maria Buccoliero, Flavio Giordano, Felix Rosenow, Katja Menzler, Rita Garbelli, , TEMPORAL-LOBE EPILEPSY; SURGICAL OUTCOMES;

Co-existence of self-limited focal epilepsies of childhood (SelFEC) and epileptiform discharges in the context of SelFEC in children with structural focal epilepsies and in children with brain lesions

H. Holthausen, A. Brockhaus, C. von Stülpnagel, T. Pieper, A. Zsoter, G. Kluger, S. Berweck, T. Hartlieb , FOLLOW-UP; SURGERY; WHITE-MATTER ABNORMALITIES; ILAE COMMISSION; CEREBRAL-PALSY; CENTROTEMPORAL SPIKES; SELECTS; Rolandic Spikes; Vascular lesions; Perinatal asphyxia; Cerebral palsy; Rolando Spikes; Vasculare Lasionen; Perinatale Asphyxie; Zerebrallahmung; ELECTRICAL STATUS EPILEPTICUS; BENIGN ROLANDIC EPILEPSY; LOBE EPILEPSY; SHARP WAVES;

Corticosteroids versus clobazam for treatment of children with epileptic encephalopathy with spike-wave activation in sleep (RESCUE ESES)

Marleen M L van Arnhem, Bart van den Munckhof, Alexis Arzimanoglou, Emilio Perucca, Liisa Metsähonkala, Guido Rubboli, Marianne Søndergaard Khinchi, Anne de Saint-Martin, Kerstin A Klotz, Julia Jacobs, J Helen Cross, Irene Garcia Morales, Wim M Otte, Heleen C van Teeseling, Frans S S Leijten, Kees P J Braun, Floor E Jansen, , Gerhard Kluger , Humans; EPILEPSY; Retrospective Studies; CHILD; Child, Preschool; METHYLPREDNISOLONE; Adrenal Cortex Hormones/therapeutic use; Clobazam; Epilepsy, Generalized;

Brain expression profiles of two SCN1A antisense RNAs in children and adolescents with epilepsy

MF Schneider, M. Vogt, J. Scheuermann, V. Müller, AHL Fischer-Hentrich, T. Kremer, S. Lugert, F. Metzger, M. Kudernatsch, G. Kluger, T. Hartlieb, S. Noachtar, C. Vollmar, M. Kunz, JC Tonn, R. Coras, I. Blümcke, C. Pace, F. Heinen, C. Klein, H. Potschka, I. Borggraefe , SURGERY; MODEL; EPILEPSY; PRECISION MEDICINE; SEIZURES; DRAVET SYNDROME; SUDDEN UNEXPECTED DEATH; long non coding RNA; regulatory RNA;

A novel GABRG2 variant in Sunflower syndrome: A case report and video EEG monitoring.

Jo Sourbron, Renee Proost, Katrien Jansen, Antonella Riva, Kirsten Eschermann, James Richard Barnett, Lieven Lagae , Humans; Male; CHILD; Anticonvulsants/therapeutic use; Electroencephalography/methods; Epilepsy, Reflex/diagnosis; Helianthus/genetics; Receptors, GABA-A; Seizures/diagnosis; Syndrome; Valproic Acid/therapeutic use;

Is ketogenic diet a 'precision medicine'? Recent developments and future challenges

R. Falsaperla, V. Sortino, P. Striano, G. Kluger, G. Ramantani, M. Ruggieri, , Humans; BRAIN; MECHANISMS; CHILDREN; Treatment Outcome; EFFICACY; PRECISION MEDICINE; ADOLESCENTS; Quality of life; KETOGENIC DIET; DRUG-RESISTANT EPILEPSY; GLUT-1; Transcriptomic profile; CHILDHOOD EPILEPSY; GLUCOSE-TRANSPORT; Diet, Ketogenic/adverse effects; Neuroinflammatory Diseases; Monosaccharide Transport Proteins/deficiency; Glucose Transporter Type 1; Epilepsy/genetics; Carbohydrate Metabolism, Inborn Errors;

Establishing PROMs in medication management of rare genetic epilepsies: what are the best medications in 228 SYNGAP1 patients?

K. Eschermann, G. Kluger, V. Schmeder, MM Hinojosa, S. Apler, C. von Stülpnagel, T. Hartlieb, D. Weghuber, L. Kiwull