Programm Experimentelle Ophthalmologie und Glaukomforschung
Publikationen

Association of lifestyle and metabolic factors with clinical performance in multiple sclerosis

Tiago Lerda-Casaccia, Josef-Martin Mitterwallner, Wolfgang Hitzl, Belinda Bohm, Janne Cadamuro, Ursula Huber-Schonauer, Michael Weichsler, Richard Friedrich Radlberger, Peter Wipfler, Tobias Moser , OUTCOMES; Employment; Multiple Sclerosis; Lipids; Lifestyle; Smoking; Vitamins;

Angiopoietin-2 and vascular endothelial growth factor α inhibition by faricimab reduces pericyte-to-myofibroblast transition and the myofibroblast phenotype in vitro

Andreas Koller, Julia Preishuber-Pflügl, Susanne Maria Migschitz, Nicola Aponi Pichler, Christian Runge, Markus Lenzhofer, Herbert Anton Reitsamer, Andrea Trost

TRPC6-Mediated Ca²⁺ Influx Activates MAPK and NFκB Signaling and Elicits Pro-Inflammatory and Catabolic Responses in Human Intervertebral Disc Cells

Janitri Venkatachala Babu, Varun Puvanesarajah, Addisu Mesfin, Jonathan P. Japa, Kevin Yoon, Mark Ehioghae, Michael G. Schrlau, Laura S. Stone, Wolfgang Hitzl, Karin Wuertz-Kozak , degenerative disc disease; Hyp9; MMPs; Calcium-dependent pathways; Cytokine regulation; Discogenic back pain; Ion channel; Neurovascular ingrowth; transient receptor potential channels (TRP channels);

Long-term results of apical prolapse correction by unilateral pectineal suspension

Cosima Veronika Maria Brucker, Dimitrios Ilias Bolovis, Michael Schreibmayer, Wolfgang Hitzl , Humans; Aged; Middle Aged; Female; Treatment Outcome; RECURRENCE; Follow-Up Studies; ADULT; Aged, 80 and over; PATIENT SATISFACTION; Pelvic Organ Prolapse/surgery; Surgical Mesh; Gynecologic Surgical Procedures/methods;

Real-Time Perfusion Assessment with Hyperspectral Imaging After Revascularization in Peripheral Artery Disease

Michaela Kluckner, Wolfgang Hitzl, Florian K Enzmann, David Wippel, Maximilian Lutz, Sabine Wipper

Autologous Osteochondral Transplantation in Large Osteochondral Defects – A Follow-Up of 40 Patients After Talus Re-Surfacing

Alice Wittig-Dränert, Martin Breitwieser, Patrick F. Marko, Wolfgang Hitzl, Jürgen Bruns

TSG-6 Activated MSC-derived Extracellular Vesicles Present Altered micro-RNA Contents and Ameliorate the Inflammatory Phenotype of Macrophages in Vitro

Iker Martinez-Zalbidea, Alyssa Rzasa, Varun Puvanesarajah, Wolfgang Hitzl, Karin Wuertz-Kozak

Development and Characterization of a Tunable PDMS Substrate Model for Investigating Elastic Properties and Mechanical Stretching in Intervertebral Disc Cells

Johannes Hasler, Mikkael Lamoca, Kory Schimmelpfennig, Shuhuan Zhang, Wolfgang Hitzl, Sami Farajollahi, Vinay V. Abhyankar, Christopher L. Lewis, Rui Liu, Karin Wuertz-kozak , SPINE; SUBSTRATE STIFFNESS; ANNULUS FIBROSUS; Strex; Sylgard 184; Sylgard 527; Cell alignment; Cell-substrate interaction; Digital image correlation; Stretching chambers;

The effect of CysLTR1 inhibition on cells of the retinal neurovascular unit in 5xFAD Alzheimer mice

Daniela Mayr, Julia Preishuber-Pflugl, Andreas Koller, Susanne M. Migschitz, Johanna Michael, Barbara Altendorfer, Roland Rabl, David Amschl, Wolfgang Hitzl, Ludwig Aigner, Herbert A. Reitsamer, Andrea Trost , PERICYTES; MICROGLIAL CELLS; NEUROVASCULAR UNIT; Alzheimer's disease; (1-7); 5xFAD mouse model; Cysteinyl leukotriene receptor 1 (CysLTR1); Montelukast;

Underexposure of linezolid in critically ill patients with extracorporeal membrane oxygenation (ECMO)

Rainer Hohl, Fabian Rasshofer, Martina Kinzig, Fritz Sorgel, Wolfgang Hitzl, Ralph Bertram, Joerg Steinmann, , PHARMACOKINETICS; Ecmo; Linezolid; Pharmacodynamics; Plasma levels; Therapeutic drug monitoring;

Is There an “Ideal” Sequencing for Open Reduction and Internal Fixation of Multiple Mandibular Fractures with Condylar Neck Involvement? A Retrospective Cohort Study

Gian Bottini, Wanda Lauth, Wolfgang Hitzl, Benjamin Walch, Maximilian Modelhart, Katharina Zeman-Kuhnert, Florian Huber, Florian Menapace, Marie-Christine Wilhelmstätter, Christoph Steiner

Prospektives internationales Register für Treatment Exit Options in Uveitis (TOFU) – die ersten 5 Jahre

Carsten Heinz, David J Fink, Jennifer Dell, Moritz Berger, Matthias Schmid, Robert P Finger, , Herbert Reitsamer, Markus Lenzhofer , Humans; Male; Aged; Prospective Studies; Middle Aged; Female; PREVALENCE; Treatment Outcome; CHILD; ADOLESCENT; ADULT; Germany/epidemiology; Young Adult; Europe/epidemiology; Uveitis/therapy; Registries/statistics & numerical data;

Cysteinyl leukotriene receptor 1 regulates cellular glucose levels in human retinal cells

Andreas Koller, Susanne Maria Brunner, Julia Preishuber-Pflügl, Daniela Mayr, Christian Runge, Herbert Anton Reitsamer, Andrea Trost , Humans; Glucose/metabolism; CELL LINE; Receptors, Leukotriene/metabolism; Retina/metabolism; Acetates/pharmacology; Quinolines/pharmacology; Leukotriene Antagonists/pharmacology; Sulfides; Cyclopropanes; Endothelial Cells/metabolism; Pericytes/metabolism; Tosyl Compounds/pharmacology; Thiazolidines/pharmacology; Retinal Pigment Epithelium/metabolism; Diabetic Retinopathy/metabolism; Indoles; Sulfonamides; Phenylcarbamates;

Automated Diabetic Retinopathy Screening in Out-patient Diabetes Care - Comparison of Two Artificial Intelligence Algorithms

Florian Maria Bauer, Annette Sauerbeck, Wolfgang Hitzl, Nick Piravej, Josef Schmidbauer , screening; Aurora; OphtAI; RetCAD; Artifical intelligence; Diabetic retinopathy;

Targeting pericytes in the retina

Julia Preishuber-Pfluegl, Susanne Maria Brunner, Wenhui Huang, Andreas Koller, Herbert A. Reitsamer, Andrea Trost , PERICYTES; Estrogen receptor; Inducible cre reporter mouse; Ng2; Retina; tdTomato;

Two Machine Learning Models to Economize Glaucoma Screening Programs

Wolfgang Hitzl, Markus Lenzhofer, Melchior Hohensinn, Herbert Anton Reitsamer

Long-term impact of oral cladribine on humoral immunity in multiple sclerosis

Marc Messner, Michael Unterhofer, Jonas Strauss, Sylvia Mink, Janne Cadamuro, Hannes Oberkofler, Wolfgang Hitzl, Peter Wipfler, Eugen Trinka, Tobias Moser

The role of duplex ultrasound surveillance after prosthetic femoropopliteal bypass

Michaela Kluckner, Wolfgang Hitzl, David Wippel, Laura Schönherr, Sabine Wipper, Leonhard Gruber, Florian K Enzmann

Effects of Cranial Electrotherapy Stimulation in Patients with Post-COVID-19 Condition on Anxiety Symptoms

Daniela Kroll, Rainer Gloeckl, Tessa Schneeberger, Inga Jarosch, Isabel Klefenz, Wolfgang Hitzl, Andreas R. Koczulla , Humans; Male; Aged; Middle Aged; Female; Treatment Outcome; ADULT; SARS-CoV-2; Pilot Projects; Double-Blind Method; COVID-19/psychology; Anxiety/therapy; Electric Stimulation Therapy/methods;

Omega-3 fatty acid supplementation modulates the gut microbiome, microglial phagocytosis and amyloid-beta plaque deposition in the APP/PS1 mouse model of Alzheimer’s disease

Barbara Altendorfer, Ariane Benedetti, Heike Mrowetz, Sabine Diechler, Alexander Popoff, Elena-Laura Gruber, Julia Preishuber-Pflügl, Andrea Trost, Ludwig Aigner