Forschung & Innovation
Publikationen

Structure-based discovery of opioid analgesics with reduced side effects.

#2016

#NATURE

PMU Autor*in
Ralf Kling

Alle Autor*innen
Aashish Manglik, Henry Lin, Dipendra K Aryal, John D McCorvy, Daniela Dengler, Gregory Corder, Anat Levit, Ralf Kling, Viachaslau Bernat, Harald Hübner, Xi-Ping Huang, Maria F Sassano, Patrick M Giguère, Stefan Löber, Da Duan, Grégory Scherrer, Brian K Kobilka, Peter Gmeiner, Bryan L Roth, Brian K Shoichet

Fachzeitschrift
NATURE

Kurzfassung

Keywords

PAIN, MODEL, IDENTIFICATION, CRYSTAL-STRUCTURE, MICE, PROTEIN-COUPLED RECEPTOR, A(2A) RECEPTOR ANTAGONISTS, MORPHINE ANALGESIA, LIGAND DISCOVERY, BIASED AGONISM

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Paracelsus Medizinische Privatuniversität Forschung & Innovation Publikationen

Structure-based discovery of opioid analgesics...