Research & Innovation
Publications

Structure-based discovery of opioid analgesics with reduced side effects.

#2016

#NATURE

PMU Author
Ralf Kling

All Authors
Aashish Manglik, Henry Lin, Dipendra K Aryal, John D McCorvy, Daniela Dengler, Gregory Corder, Anat Levit, Ralf Kling, Viachaslau Bernat, Harald Hübner, Xi-Ping Huang, Maria F Sassano, Patrick M Giguère, Stefan Löber, Da Duan, Grégory Scherrer, Brian K Kobilka, Peter Gmeiner, Bryan L Roth, Brian K Shoichet

Journal association
NATURE

Abstract

Keywords

PAIN, MODEL, IDENTIFICATION, CRYSTAL-STRUCTURE, MICE, PROTEIN-COUPLED RECEPTOR, A(2A) RECEPTOR ANTAGONISTS, MORPHINE ANALGESIA, LIGAND DISCOVERY, BIASED AGONISM

Latest Publication

#2026

#Original Article

Xinxin Zhu, Yi Yang, Helen Wright, Lydia Gabriela Speyer, Marie Allitt, Ingrid Obsuth, Patrick Errington, Aja Louise Murray The association between social media use and mental health symptoms in middle adolescence, SUICIDE ATTEMPTS; SELF-HARM; adolescence; Counterfactual analysis; Emotional symptoms; Social media use;

#2026

#Abstract

Lara Sophie Bieler Therapeutic MSC-EV delivery and iNSC transplantation for spinal cord injury repair

#2026

#Original Article

Fabrizio Rinaldi, Bruna Nucera, Sara Mariozzi, Eleonora Leuci, Arianna Bratti, Wolfgang Hitzl, Luigi Ferini-Strambi, Eugen Trinka, Kneginja Richter Impact of Chronotype-Based scheduling on sleep EEG in first seizure Patients

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Paracelsus Medical Private University (PMU) Research & Innovation Publications

Structure-based discovery of opioid analgesics...