Institut für Molekulare Regenerative Medizin
Publikationen

The effect of CysLTR1 inhibition on cells of the retinal neurovascular unit in 5xFAD Alzheimer mice

Daniela Mayr, Julia Preishuber-Pflugl, Andreas Koller, Susanne M. Migschitz, Johanna Michael, Barbara Altendorfer, Roland Rabl, David Amschl, Wolfgang Hitzl, Ludwig Aigner, Herbert A. Reitsamer, Andrea Trost , PERICYTES; MICROGLIAL CELLS; NEUROVASCULAR UNIT; Alzheimer's disease; (1-7); 5xFAD mouse model; Cysteinyl leukotriene receptor 1 (CysLTR1); Montelukast;

The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain

Marco Zattoni, Sabine Bernegger, Sofia Weinbender, Barbara Altendorfer, Heike Mrowetz, Ariane Benedetti, Rodolphe Poupardin, Michael Stefan Unger, Ludwig Aigner , Humans; Animals; MICE; Mice, Transgenic; Brain/metabolism; Alzheimer Disease/pathology; Disease Models, Animal; Microglia/metabolism; Chemokine CXCL16/metabolism; Receptors, CXCR6/metabolism; CD8-Positive T-Lymphocytes/metabolism; Organic Chemicals;

Evolution of MRI Parameters from the Subacute to Chronic Phase After Human Traumatic Cervical Spinal Cord Injury

Andreas Grillhoesl, Iris Leister, Florian Hoegel, Ludwig Sanktjohanser, Matthias Vogel, Orpheus Mach, Doris Maier, Lukas Grassner , Biomarker; Magnetic resonance imaging; Spinal cord injury; Diffusion Tensor Imaging;

Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study

Katharina Strempfl, Marco Zattoni, Heike Mrowetz, Michael S Unger, Nikolaos Schörghofer, Barbara Altendorfer, Jörg Neddens, Stefanie Flunkert, Birgit Hutter-Paier, Yachao He, Johan Wallin, Rodolphe W Poupardin, Frank Pietrantonio, Nadine Paiement, Horst Zerbe, Thomas Felder, Per Svenningsson, Ludwig Aigner

Exploring the impact of SerpinA3n deficiency on prion strains propagation

Fabio Moda, Chiara Ferracin, Ilaria Linda Dellarole, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Marco Zattoni, Diletta Giovanna Legari, Lea Nikolic, Anna Burato, Martina Brce, Giuseppe Bufano, Merve Beguem Bacinoglu, Federico Angelo Cazzaniga, Tihana Lenac Rovis, Giuseppe Legname

Translational Pitfalls in SCI Bladder Research: The Hidden Role of Urinary Drainage Techniques in the Rat Model

Sophina Bauer, Michael Kleindorfer, Karin Roider, Evelyn Beyerer, Martha Georgina Brandtner, Peter Törzsök, Lukas Lusuardi, Ludwig Aigner, Elena Esra Keller

Long-Term Management and Monitoring of the Bladder After Spinal Cord Injury in a Rodent Model

Michael Kleindorfer, Karin Roider, Evelyn Beyerer, Sophina Bauer, Patrick Heimel, David Hercher, Martha Georgina Brandtner, Lukas Lusuardi, Ludwig Aigner, Elena Esra Keller

Omega-3 fatty acid supplementation modulates the gut microbiome, microglial phagocytosis and amyloid-beta plaque deposition in the APP/PS1 mouse model of Alzheimer’s disease

Barbara Altendorfer, Ariane Benedetti, Heike Mrowetz, Sabine Diechler, Alexander Popoff, Elena-Laura Gruber, Julia Preishuber-Pflügl, Andrea Trost, Ludwig Aigner

Bryostatin-1 modulates microglial activation and neuroregeneration in in vitro models of spinal cord injury

Sofia Chanel Weinbender, Marco Zattoni, Bruno Benedetti, Mathias Nöbauer, Teresa Pfau, Moritz Brosch, Viktor Lippert, Lara Sophie Bieler, Ariane Benedetti, Sébastien Couillard-Després, Ludwig Aigner

Blood serum from individuals with Alzheimer's disease alters microglial phagocytosis in vitro

Barbara Altendorfer, Rodolphe Poupardin, Sophie Lefèvre-Arbogast, Claudine Manach, Dorrain Y Low, Mireia Urpi-Sarda, Cristina Andres-Lacueva, Raúl González-Domínguez, Thomas K Felder, Julia Tevini, Marco Zattoni, Andreas Koller, Reinhold Schmidt, Paul J Lucassen, Silvie R Ruigrok, Chiara de Lucia, Andrea Du Preez, Catherine Helmer, Jeanne Neuffer, Cécile Proust-Lima, Aniko Korosi, Cécilia Samieri, Sandrine Thuret, Ludwig Aigner

Montelukast Improves Urinary Bladder Function After Complete Spinal Cord Injury in Rats

Elena E Keller, Sophina Bauer, Karin Roider, Michael Kleindorfer, Peter Törzsök, Julia Tevini, Thomas Felder, Ludwig Aigner, Lukas Lusuardi , Female; Animals; RATS; Disease Models, Animal; Pilot Projects; Acetates/pharmacology; Quinolines/pharmacology; Cyclopropanes/pharmacology; Sulfides/pharmacology; Leukotriene Antagonists/pharmacology; Spinal Cord Injuries/drug therapy; Urinary Bladder/drug effects; Urinary Bladder, Neurogenic/drug therapy; Rats, Inbred Lew;

Long-Term Management and Monitoring of the Bladder After Spinal Cord Injury in a Rodent Model

Michael Kleindorfer, Elena Esra Keller, Karin Roider, Evelyn Beyerer, Patrick Heimel, David Hercher, Martha Georgina Brandtner, Lukas Lusuardi, Ludwig Aigner, Sophina Bauer , 3r; Animal model; Neurogenic bladder; neurogenic lower urinary tract dysfunction (nLUTD); spinal cord injury (SCI);

Omega-3 EPA Supplementation Shapes the Gut Microbiota Composition and Reduces Major Histocompatibility Complex Class II in Aged Wild-Type and APP/PS1 Alzheimer’s Mice: A Pilot Experimental Study

Barbara Altendorfer, Ariane Benedetti, Heike Mrowetz, Sabine Bernegger, Alina Bretl, Julia Preishuber-Pflügl, Diana Marisa Bessa de Sousa, Anja Maria Ladek, Andreas Koller, Pauline Le Faouder, Justine Bertrand-Michel, Andrea Trost, Ludwig Aigner

Regulation of NK cell development, maturation, and antitumor responses by the nuclear receptor NR2F6

Johannes Woelk, Florian Hornsteiner, Stephanie Aschauer-Wallner, Patrizia Stoitzner, Gottfried Baier, Natascha Hermann-Kleiter , ACTIVATION; EXPRESSION; RECOGNITION; NATURAL-KILLER-CELLS; Nkp46;

Early Sacral Neuromodulation

Sophina Bauer, Lukas Grassner, Doris Maier, Ludwig Aigner, Lukas Lusuardi, Julia Peters, Orpheus Mach, Karin Roider, Evelyn Beyerer, Michael Kleindorfer, Andreas Wolff, Iris Leister, Elena E Keller

Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice

Andreas Koller, Julia Preishuber-Pflügl, Daniela Mayr, Susanne Maria Brunner, Anja-Maria Ladek, Christian Runge, Ludwig Aigner, Herbert Anton Reitsamer, Andrea Trost , Male; Animals; MICE; Proteasome Endopeptidase Complex/metabolism; Mice, Inbred C57BL; Microglia/drug effects; Proteolysis/drug effects; Receptors, Leukotriene/metabolism; Aging/metabolism; Retina/metabolism; Acetates/pharmacology; Quinolines/pharmacology; Cyclopropanes/pharmacology; Retinal Vessels/drug effects; Sulfides/pharmacology; Leukotriene Antagonists/pharmacology;

APP/PS1 MOUSE DERIVED PLATELET HOMOGENATES CONVEY STRUCTURAL AND FUNCTIONAL HIPPOCAMPAL DYSFUNCTIONS IN HEALTHY YOUNG MICE

Heike Mrowetz, Kathrin Maria Drerup, Adam Schroer, Gregor Bieri, Saul A Villeda, Ludwig Aigner

Omega-3 fatty acid supplementation modulates the gut microbiome, microglial phagocytosis and amyloid-beta plaque deposition in the APP/PS1 mouse model of Alzheimer’s disease

Barbara Altendorfer, Ariane Benedetti, Heike Mrowetz, Sabine Diechler, Alexander Popoff, Elena-Laura Gruber, Julia Preishuber-Pflügl, Andrea Trost, Ludwig Aigner

OMEGA-3 FATTY ACID EPA SUPPLEMENTATION RESTORES GUT MICROBIOTA BALANCE IN THE APP-PS1 MOUSE MODEL OF ALZHEIMER'S DISEASE

Barbara Altendorfer, Heike Mrowetz, Ariane Benedetti, Alina Bretl, Diana Marisa Bessa de Sousa, Anja Maria Ladek, Andreas Koller, Andrea Zurl, Ludwig Aigner

Short-term CD8+ T cell ablation reduces dystrophic neurites in the brain of aged APP/PS1 animals

Marco Zattoni, Sabine Diechler, Marijana Maksimovic, Sophie-Marie Rieder, Barbara Altendorfer, Heike Mrowetz, Ariane Benedetti, Jennifer Forster, Michael Stefan Unger, Ludwig Aigner