Institut für Pharmazie
Publikationen

Treatment of Parkinson's Disease Psychosis-A Systematic Review and Multi-Methods Approach

Olaf Rose, Sophia Huber, Eugen Trinka, Johanna Pachmayr, Stephanie Clemens , CLOZAPINE; Systematic review; Survey; Pharmacotherapy; Parkinson's disease psychosis; Multi-methods; Pimavanserin; Quetiapine;

FREEING ENERGY: A CASE STUDY COMPARING ACCURACY AND EFFICIENCY OF ADVANCED MOLECULAR DYNAMICS METHODS WITH CHEAPER END-POINT METHODS

Moritz-Connor Schulte, Monika Pintar-Hitzl, Daniela Brigitte Schuster, Veronika Temml

Impact of 2-hydroxypropyl-β-cyclodextrin inclusion complex formation on dopamine receptor-ligand interaction - A case study

Lukas Zell, Thomas S. Hofer, Mario Schubert, Alexander Popoff, Anna Hoell, Moritz Marschhofer, Petra Huber-Cantonati, Veronika Temml, Daniela Schuster , 2-hydroxypropyl-beta-cyclodextrin; Dopamine receptor ligands; In silico; In vitro; Inclusion complex; Semi-empirical quantum chemistry;

Artificial intelligence to assist decision-making on pharmacotherapy

Michael Buecker, Kreshnik Hoti, Olaf Rose , Artificial Intelligence; Cardiology; Clinical decision support system; Medication review; Pharmacotherapy; Pharmacy practice;

Discovery of the Pendulisporaceae

Ronald Garcia, Alexander Popoff, Chantal D. Bader, Johanna Loehr, Sebastian Walesch, Christine Walt, Judith Boldt, Boyke Bunk, F. P. Jake Haeckl, Antonia P. Gunesch, Joy Birkelbach, Ulrich Nuebel, Thomas Pietschmann, Thorsten Bach, Rolf Mueller , BIOLOGY; BIOSYNTHESIS; GENES; MECHANISM; ANTIBIOTICS; CLUSTER; PERSPECTIVE; NATURAL-PRODUCTS; Streptomyces; Sorangicin;

A validated HPLC-MS/MS method for the quantification of systemic mifepristone after subcutaneous application in mice

Julia Tevini, Sepideh Aminzadeh-Gohari, Daniela D Weber, Luca Catalano, Victoria E Stefan, Elisa Redl, Chiara Herzog, Roland Lang, Martin Widschwendter, Thomas K Felder, Barbara Kofler

Drug-related problems in elective surgical inpatients: A retrospective study

Clara Simon, Olaf Rose, Karin Kanduth, Johanna Pachmayr, Stephanie Clemens

FROM LAPTOP TO TOP-LAB: A COMBINED IN SILICO IN VITRO APPROACH TO IDENTIFY NOVEL MICROTUBULE STABILIZERS AS POTENTIAL DRUG CANDIDATES

Florian Fischer, Daniela Brigitte Schuster, Veronika Temml

Melatonin in Human Breast Milk and Its Potential Role in Circadian Entrainment

Silke Häusler, Emma Lanzinger, Elke Sams, Claudius Fazelnia, Kevin Allmer, Christoph Binder, Russel J. Reiter, Thomas K. Felder , Humans; Female; Melatonin/metabolism; Milk, Human/chemistry; Circadian Rhythm/physiology; Breast Feeding; Infant, Newborn; Lactation/physiology; Infant Nutritional Physiological Phenomena/physiology;

Determination of Hyaluronidase Binding Free Energy using Advanced Molecular Dynamic Methods

Moritz-Connor Schulte, Monika Pintar-Hitzl, Daniela Brigitte Schuster, Veronika Temml

Effects of medication management in geriatric patients who have fallen

Stephanie Clemens, Bernhard Iglseder, Reinhard Alzner, Magdalena Kogler, Olaf Rose, Patrick Kutschar, Simon Krutter, Karin Kanduth, Christina Dückelmann, Maria Flamm, Johanna Pachmayr , Humans; Aged; AFTERCARE; Fractures, Bone; Accidental Falls/prevention & control; Medication Therapy Management; Patient Discharge;

Correlation of Experimental and Calculated Inhibition Constants of Protease Inhibitor Complexes

Peter Goettig, Xingchen Chen, Jonathan M Harris , Serine Endopeptidases; Trypsin Inhibitors/pharmacology; Trypsin/metabolism; Helianthus/metabolism; Peptide Hydrolases; Protease Inhibitors/pharmacology;

Exciting Times – Employing Time-Dependent Density Functional Theory in Describing Triplet Excited States of Natural Products

Moritz-Connor Schulte, Bianka Siewert, Yurii Husiev, Sylvestre Bonnet, Daniela Brigitte Schuster, Veronika Temml

FROM PROPHECY TO REALITY: NAVIGATING MICROTUBULE DYNAMICS VIA PHARMACOPHORE MODELS AND IN VITRO EXPEDITION

Florian Fischer, Daniela Brigitte Schuster, Veronika Temml

Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer

D. Macejova, J. Kollar, P. Bobal, J. Otevrel, D. Schuster, J. Brtko , ACTIVATION; APOPTOSIS; DEATH; ASSAY; ACID; ENDOCRINE; Triorganotin isoselenocyanates; Retinoid X receptor; Breast cancer; ORGANOTIN COMPOUND; ANTITUMOR-ACTIVITY; ACCURATE DOCKING; GLIDE;

Entwicklung und Validierung eines digitalen Tools (mediPORT) zur Vorhersage von arzneimittel-bezogenen Problemen bei elektiv zu operierenden Patient*innen

Stephanie Clemens, Clara Simon, Wanda Lauth, Olaf Rose, Georg Johannes Zimmermann, Peter Gerner, Christina Dückelmann, Maria Flamm, Johanna Pachmayr

Structural and clinical characterization of CYP11B2 inhibition by dexfadrostat phosphate

E. Pignatti, J. Kollar, E. Hafele, D. Schuster, RE Steele, B. Vogt, C. Schumacher, M. Groessl , VALIDATION; ALDOSTERONE; CORTISOL; GENETIC ALGORITHM; Dexfadrostat phosphate; AROMATASE INHIBITORS; CGS-16949A;

Safety first? Drug-related problems at admission to surgery: A retrospective study

Stephanie Clemens

Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach.

Mark James Horgan, Lukas Zell, Bianka Siewert, Hermann Stuppner, Daniela Brigitte Schuster, Veronika Temml , Prospective Studies; Structure-Activity Relationship; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Cell Proliferation; Colchicine/pharmacology; Drug Screening Assays, Antitumor; Molecular Structure; Tubulin Modulators/pharmacology; Tubulin/metabolism;

Cost-effectiveness of granulocyte colony-stimulating factors (G-CSFs) for the prevention of febrile neutropenia (FN) in patients with cancer

Matti S. Aapro, Stephen Chaplin, Paul Cornes, Sebastian Howe, Hartmut Link, Natalia Koptelova, Andrea Mehl, Mario Di Palma, Bridgette Kanz Schroader, Robert Terkola , RISK; METAANALYSIS; RECOMMENDATIONS; SURVIVAL; COST-EFFECTIVENESS; CHEMOTHERAPY; GROWTH-FACTORS; Febrile neutropenia; Filgrastim; Biosimilar; Pegfilgrastim; STAGE BREAST-CANCER; PRIMARY PROPHYLAXIS; DOCETAXEL; REDUCE;