Paracelsus Medizinische Privatuniversität (PMU)

Research & Innovation
Publications

Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammation.

#2022
#BIOCHEMICAL PHARMACOLOGY

PMU Authors
Veronika Temml, Daniela Brigitte Schuster

All Authors
Verena Krauth, Ferdinando Bruno, Simona Pace, Paul M Jordan, Veronika Temml, Maria Preziosa Romano, Haroon Khan, Daniela Brigitte Schuster, Antonietta Rossi, Rosanna Filosa, Oliver Werz

Journal association
BIOCHEMICAL PHARMACOLOGY

Abstract

Keywords

Humans, Animals, IRON, MICE, HEK293 Cells, DERIVATIVES, FLAVONOIDS, ARACHIDONIC-ACID RELEASE, LEUKOTRIENE BIOSYNTHESIS, INTERFERENCE, PRODUCTS, ZILEUTON, Catechols/pharmacology, Arachidonate 5-Lipoxygenase/metabolism, Lipoxygenase Inhibitors/pharmacology, Inflammation/drug therapy