Paracelsus Medizinische Privatuniversität (PMU)

Research & Innovation
Publications

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.

#2020
#CELL

PMU Author
Sandra Erichsen

All Authors
Markus Hoffmann, Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Tanja Herrler, Sandra Erichsen, Tobias S Schiergens, Georg Herrler, Nai-Huei Wu, Andreas Nitsche, Marcel A Müller, Christian Drosten, Stefan Pöhlmann

Journal association
CELL

Abstract

Keywords

INFECTION, LUNG, VIRUS, ACUTE RESPIRATORY SYNDROME, ANGIOTENSIN-CONVERTING ENZYME-2, SARS-ASSOCIATED CORONAVIRUS, TO-HUMAN TRANSMISSION, SPIKE PROTEIN, FUNCTIONAL RECEPTOR, S-PROTEIN