Institut für Experimentelle und Klinische Zelltherapie
Publikationen

The involvement of microglia and the CXCL16-CXCR6 axis in the recruitment of CD8+ T cells to an amyloidogenic mouse brain

Marco Zattoni, Sabine Bernegger, Sofia Weinbender, Barbara Altendorfer, Heike Mrowetz, Ariane Benedetti, Rodolphe Poupardin, Michael Stefan Unger, Ludwig Aigner , Humans; Animals; MICE; Mice, Transgenic; Brain/metabolism; Alzheimer Disease/pathology; Disease Models, Animal; Microglia/metabolism; Chemokine CXCL16/metabolism; Receptors, CXCR6/metabolism; CD8-Positive T-Lymphocytes/metabolism; Organic Chemicals;

Prime editing as a promising therapeutic strategy for junctional epidermolysis bullosa

Markus Hierl, Johannes Bischof, Bernadette Liemberger, Thomas Kocher, Stefan Hainzl, Stefanie Gruner, Lisa Trattner, Victoria Reichl, Alfred Klausegger, Clotilde Aussel, Sandra Ammann, Rebecca Raab, Geoffroy Andrieux, Martin Wolf, Sarah Hochmann, Patricia Ebner, Verena Wally, Roland Zauner, Christina Guttmann-Gruber, Iris K Gratz, Josefina Piñón Hofbauer, Toni Cathomen, Dirk Strunk, Johann W Bauer, Ulrich Koller

The Use of Piper amalago var. amalago as an Eco-Friendly Insecticide Synergist in the Management of Aedes Aegypti

Chelsea Frank, Dwight Robinson, Rodolphe Poupardin, William Irvine, Mark J. I. Paine, Rupika Delgoda, Sheena Francis , INHIBITION; RESISTANCE; MEDICINES; MOLECULAR-DYNAMICS; TEMPERATURE; NATURAL-PRODUCTS; Vector-borne diseases; Essential oils; Methylenedioxyphenyl; Amides;

Selective EV Protein Sorting and Pathway Perturbation in AML Upon Synergistic FLT3 and Hedgehog Pathway Inhibition

C. Blöchl, Gabriele Blümel, Martin Wolf, G. Regl, Heide-Marie Binder, Suzana Tesanovic, Daniel Lankes, Nicole Maeding, P. Krenn, Dirk Strunk, Fritz Aberger, Christian G Huber

Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study

Katharina Strempfl, Marco Zattoni, Heike Mrowetz, Michael S Unger, Nikolaos Schörghofer, Barbara Altendorfer, Jörg Neddens, Stefanie Flunkert, Birgit Hutter-Paier, Yachao He, Johan Wallin, Rodolphe W Poupardin, Frank Pietrantonio, Nadine Paiement, Horst Zerbe, Thomas Felder, Per Svenningsson, Ludwig Aigner

Quantitative characterisation of extracellular vesicles designed to decoy or compete with SARS-CoV-2 reveals differential mode of action across variants of concern and highlights the diversity of Omicron

Melanie Schuerz, Isabel Pagani, Eva Klinglmayr, Heloisa Melo Benirschke, Martin Mayora Neto, Luis J. V. Galietta, Arianna Venturini, Nicoletta Pedemonte, Valeria Capurro, Sandra Laner-Plamberger, Christoph Grabmer, Essi Emminger, Martin Wolf, Marianne Steiner, Cyrus Kohlmetz, Niklas Mayr, Liliia Paniushkina, Katharina Schallmoser, Dirk Strunk, Hans Brandstetter, Martin Hintersteiner, Nigel Temperton, Elisa Vicenzi, Nicole Meisner-Kober , PROTEIN; CELLS; CORONAVIRUS; Ace2; Spike;

T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients

Lisa Weidner, Rodolphe Poupardin, Tobias Zrzavy, Sandra Laner-Plamberger, Georg Gratz, Tanja Eichhorn, Viktoria Weber, Paulus S. Rommer, Christof Jungbauer, Dirk Strunk , NEUROSCIENCE; Multiple Sclerosis; T cell repertoire; Bioinformatics; Cytokine imbalance;

Blood serum from individuals with Alzheimer's disease alters microglial phagocytosis in vitro

Barbara Altendorfer, Rodolphe Poupardin, Sophie Lefèvre-Arbogast, Claudine Manach, Dorrain Y Low, Mireia Urpi-Sarda, Cristina Andres-Lacueva, Raúl González-Domínguez, Thomas K Felder, Julia Tevini, Marco Zattoni, Andreas Koller, Reinhold Schmidt, Paul J Lucassen, Silvie R Ruigrok, Chiara de Lucia, Andrea Du Preez, Catherine Helmer, Jeanne Neuffer, Cécile Proust-Lima, Aniko Korosi, Cécilia Samieri, Sandrine Thuret, Ludwig Aigner

Spexin expression in the human bile duct and perihilar cholangiocarcinoma

Sara Huber, Theresia Fitzner, Rene G. Feichtinger, Theo Kraus, Stefanie Gaisbauer, Sarah Hochmann, Karl Sotlar, Barbara Kofler, Martin Varga , NEUROPEPTIDES; SPEXIN; CHOLANGIOCARCINOMA; Cholestasis; Bile duct; Cholangiocytes;

Human Cardiac Microtissues Display Improved Engraftment and Survival in a Porcine Model of Myocardial Infarction

Evelyne Demkes, Aina Cervera-Barea, Patricia Ebner-Peking, Martin Wolf, Sarah Hochmann, Amy S Scheren, Mayke Bijsterveld, C Marlies van Oostveen, Marlijn Jansen, Joyce Visser, Wiebke Triebert, Caroline Halloin, Johannes G G Dobbe, Judith de Vos, Melanie Schürz, Joachim Danmayr, Maurice C G Aalders, Gerard J J Boink, Klaus Neef, Dirk Strunk, Robert Zweigerdt, Saskia C A de Jager, Joost P G Sluijter

Anatomical variations and their association with carpal tunnel syndrome

Michaela Gruber, Agnes Wawrik, Florin Gasser, Barbara Ebner, Philipp Reitbauer, Robert Uzel, Rodolphe Poupardin, Maximilian Mahrhofer, Laurenz Weitgasser, Karl Schwaiger, Gottfried Schaffler, Gottfried Wechselberger, Elisabeth Russe , ULTRASOUND; Anatomical variations; Bifid median nerve; Carpal tunnel syndrome; Persistent arteria mediana; Persistent median artery;

Efficient correction of a prevalent COL7A1 mutation via prime editing in recessive dystrophic epidermolysis bullosa

J. Bischof, T. Kocher, L. Lopes Pedroso, B. Liemberger, S. Hainzl, M. Hierl, N. Maeding, D. Strunk, C. Guttmann-Gruber, V. Wally, J. Pinon Hofbauer, J. W. Bauer, U. Koller

DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders

Ivana Lessel, Anja Baresic, Ivan K Chinn, Jonathan May, Anu Goenka, Kate E Chandler, Jennifer E Posey, Alexandra Afenjar, Luisa Averdunk, Maria Francesca Bedeschi, Thomas Besnard, Rae Brager, Lauren Brick, Melanie Brugger, Theresa Brunet, Susan Byrne, Oscar de la Calle-Martín, Valeria Capra, Paul Cardenas, Céline Chappé, Hey J Chong, Benjamin Cogne, Erin Conboy, Heidi Cope, Thomas Courtin, Wallid Deb, Robertino Dilena, Christèle Dubourg, Magdeldin Elgizouli, Erica Fernandes, Kristi K Fitzgerald, Silvana Gangi, Jaya K George-Abraham, Muge Gucsavas-Calikoglu, Tobias B Haack, Medard Hadonou, Britta Hanker, Irina Hüning, Maria Iascone, Bertrand Isidor, Irma Järvelä, Jay J Jin, Alexander A L Jorge, Dragana Josifova, Ruta Kalinauskiene, Erik-Jan Kamsteeg, Boris Keren, Nicole Maeding, Dirk Strunk, Davor Lessel , CELLS; ARCHITECTURE; DIFFERENTIATION; MUTATIONS; Checkpoint; Transcription factor bcl11b;

Evaluating the potential of Kalanchoe pinnata, Piper amalago amalago, and other botanicals as economical insecticidal synergists against Anopheles gambiae

Sheena Francis, William Irvine, Lucy Mackenzie-Impoinvil, Lucrecia Vizcaino, Rodolphe Poupardin, Audrey Lenhart, Mark J. I. Paine, Rupika Delgoda , RNA-SEQ; INSECTICIDE; Cyp; Jamaican plants; Kalanchoe (Bryophyllum) pinnata; Mosquitoes; Piper amalago var. amalago; Synergist;

Response of activated microglia to MSC-derived EVs obtained from various isolation protocols

Lara Sophie Bieler, Rodolphe Poupardin, Fabian Blessing, Eva Grasmann, Daniela Auer, Tanja Schally, Stefan Rund, Carina Anna Kals, Christina Folie, Elisabeth Bayer, Eva Rohde, Mario Gimona, Sébastien Couillard-Després

The Cdk inhibitor dinaciclib as a promising anti-tumorigenic agent in biliary tract cancer

Celina Ablinger, Daniel Neureiter, Theresa Mähr, Christian Mayr, Tobias Kiesslich, Nicole Maeding, Irina Valenta, Maximilian Ardelt, Fabian Wilhelm, Elen Neureiter, Markus Ritter, Johanna Pachmayr, Petra Huber-Cantonati , Humans; Cell Proliferation/drug effects; Antineoplastic Agents/pharmacology; Cell Line, Tumor; Biliary Tract Neoplasms/drug therapy; Pyridinium Compounds/pharmacology; Indolizines/pharmacology; Cyclic N-Oxides/pharmacology; Bridged Bicyclo Compounds, Heterocyclic/pharmacology; Apoptosis/drug effects; Cyclin-Dependent Kinases/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Cell Survival/drug effects;

Lack of Effect of Platelet- and Stromal Cell-derived EVs on Inflammation-induced 3D Chondrogenesis

Marko Morávek, Martin Wolf, Sarah Hochmann, Nicole Maeding, Luciana Lopes Pedroso, Antri Stefani, Janine Zwicklhuber, Anna Raninger, Katharina Schallmoser, Dirk Strunk

Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis

Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Bloechl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck , APOPTOSIS; Acute myeloid leukemia; Perk; eIF2 alpha, NLRP3;

BEATS - MIGRANE

Janine Zwicklhuber, Sarah Hochmann, Antri Stefani, Martin Wolf, Rodolphe Poupardin, Nicole Maeding, Stefan Leis, Daniela Weber, Julia Tevini, Barbara Kofler, Elisabeth Russe, Dirk Strunk

Advances in Extracellular Vesicle Research Over The Past Decade

Rodolphe Poupardin, Martin Wolf, Nicole Maeding, Liliia Paniushkina, Sven Geissler, Paolo Bergese, Kenneth W Witwer, Katharina Schallmoser, Gregor Fuhrmann, Dirk Strunk